PREFACE: No period in the history of organic chemistry has been as dynamic and productive
of research accomplishment as the twelve years between the completion of the first and …

Publisher Summary This chapter discusses the use of standard and well-established
procedures of rapid and efficient site-specific mutagenesis without phenotypic selection in …

A study was conducted to determine the fidelity of DNA synthesis catalyzed in vitro by the
reverse transcriptase from a human immunodeficiency virus type 1 (HIV-1). Like other retroviral …

Background: Researchers of sickle cell disease have traditionally used health care utilization
as a proxy for pain and underlying vaso-occlusion. However, utilization may not completely …

From the preface: This brief book is the outgrowth of some forty lectures in which it was attempted
to explain the phenomenon of nuclear magnetic resonance absorption and the uses of …

VI (as the dibenzenesulfonamide) and VII (as barium carbonate) had respectively 51.8±1%
and 43.1±. 1% of the radioactivity of V (as the semicarbazone or 2, 4-dinitrophenylhydrazone)…

Background Sickle cell disease (SCD) is a chronic disease associated with high degrees of
morbidity and increased mortality. Health-related quality of life (HRQOL) among adults with …

DNA-dependent DNA synthesis in vitro by human immunodeficiency virus-1 reverse
transcriptase is relatively error-prone. The enzyme, whether recombinant or from virus particles, …

Importance Zoledronic acid, a third-generation aminobisphosphonate, reduces the incidence
of skeletal-related events and pain in patients with bone metastases. The optimal dosing …

A number of reactions havebeen investigated which leadto interconversion of cyclobutyl,
cyclopropylcarbinyl and allylcarbinyl derivatives. Some degree of interconversion was …