xCELLigence system for real-time label-free monitoring of growth and viability of cell lines from hematological malignancies

…, M Navarro-Palou, T Ros, JC Amat… - OncoTargets and …, 2014 - Taylor & Francis
The xCELLigence system is a new technological approach that allows the real-time cell
analysis of adherent tumor cells. To date, xCELLigence has not been able to monitor the growth …

Yondelis®(ET-743, Trabectedin) sensitizes cancer cell lines to CD95-mediated cell death: New molecular insight into the mechanism of action

…, JM Plazas, O Vögler, A Gutiérrez, JC Amat… - European journal of …, 2011 - Elsevier
Trabectedin, a naturally occurring substance isolated from the Caribbean marine invertebrate
Ecteinascidia turbinata, is the active compound of the antitumor drug Yondelis®. The …

Fluorescence resonance energy transfer-based real-time polymerase chain reaction method without DNA extraction for the genotyping of F5, F2, F12, MTHFR, and …

…, A Nicolàs, A Gutierrez, T Ros, JC Amat… - Journal of blood …, 2014 - Taylor & Francis
Blood samples are extensively used for the molecular diagnosis of many hematological
diseases. The daily practice in a clinical laboratory of molecular diagnosis in hematology …

[HTML][HTML] Acute lymphoblastic leukemia with e1a3 BCR/ABL fusion protein. A report of two cases

…, R Ramos, J Lladó, M Sánchez, JC Amat… - … hematology & oncology, 2015 - Springer
B Acute Lymphoblastic leukemia (B-ALL) with Philadelphia chromosome (Ph′) is a neoplasm
of lymphoblast committed to the B cell lineage. The clinical presentation of B-ALL Ph′+ …

Inhibition of c-Myc down-regulation by sustained extracellular signal-regulated kinase activation prevents the antimetabolite methotrexate-and gemcitabine-induced …

…, T Ros, C Saus, J Gines, A Sampol, JC Amat… - Molecular …, 2008 - ASPET
Non-small-cell lung cancer (NSCLC) is characterized by severe resistance to chemotherapy.
Here, we demonstrate that A549 adenocarcinoma cells permanently differentiate with the …

Four-channel asymmetric Real-Time PCR hybridization probe assay: A rapid pre-screening method for critical BCR-ABL kinase domain mutations

…, A Gutiérrez, TF Marcús, S Soverini, JC Amat… - Clinical …, 2012 - Elsevier
OBJECTIVES: Within the laboratory protocols, used for the study of BCR-ABL resistance
mutations in chronic myeloid leukemia patients treated with Imatinib, direct sequencing remains …

[PDF][PDF] Inhibition of c-Myc down-regulation by sustained ERK activation prevents the antimetabolite methotrexate-and gemcitabine-induced differentiation in non-small …

…, T Ros, C Saus, J Gines, A Sampol, JC Amat… - Molecular …, 2008 - Citeseer
Non-small cell lung cancer (NSCLC) is characterized by severe resistance to chemotherapy.
Here, we demonstrate that A549 adenocarcinoma cells permanently differentiate with the …

A new family of means: the generalized weighted power means and applications

S Amat, I Jiménez, J Ruiz, J Carlos Trillo… - International Journal of …, 2023 - Taylor & Francis
Our aim is to define a new mean having specific properties which are crucial in several
applications. As examples of this kind of applications, we can mention subdivision and …

[HTML][HTML] NK and T-Cell Status as Well as Their Perforin Expression Is Related to Clinical Severity and Outcome in Difuse Large Cell Lymphoma.

…, J Martinez, C Ballester, C Crespi, MD Bea, JC Amat… - Blood, 2007 - Elsevier
A variable degree of immune impairment is present in lymphomas, either as a cause or a
consequence of the disease. There is preliminary evidence that this immune status is related to …

Primary prophylaxis of invasive fungal infections with posaconazole or itraconazole in patients with acute myeloid leukaemia or high‐risk myelodysplastic syndromes …

…, M Calabuig, JC Hernández‐Boluda, P Amat… - Mycoses, 2018 - Wiley Online Library
This is an observational‐retrospective study comparing the real‐world outcomes associated
with posaconazole vs itraconazole as prophylaxis treatments. Two hundred and ninety‐…