User profiles for K Liliom

Karoly Liliom

Department of Biophysics and Radiation Biology
Verified email at med.semmelweis-univ.hu
Cited by 3150

[HTML][HTML] Identification of Edg1 receptor residues that recognize sphingosine 1-phosphate

…, Z Lorincz, DJ Fischer, DL Baker, K Liliom… - Journal of Biological …, 2000 - ASBMB
… It should be noted that this result is not in conflict with the radioligand binding assay, which
was performed at an 8-fold lower concentration than the 8.1 nm K d for SPP on the Edg1 …

Sphingosylphosphocholine is a naturally occurring lipid mediator in blood plasma: a possible role in regulating cardiac function via sphingolipid receptors

K LILIOM, G SUN, M BÜNEMANN, T VIRÁG… - Biochemical …, 2001 - portlandpress.com
… Blood plasma and serum contain factors that activate inwardly rectifying GIRK1\GIRK4 K+ …
the plasma and serum factors responsible for activating the inwardly rectifying K+ channel …

Synthesis, structure− activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activators of PPARγ, and …

…, R Tsukahara, S Yasuda, K Liliom… - Journal of medicinal …, 2005 - ACS Publications
… 3 with a very weak inhibitory effect on LPA 2 with K i values 250 nM, 360 nM, and 5.6 μM, …
our intracellular Ca 2+ monitoring system, we obtained similar K i values for LPA 1 (425 nM) …

[HTML][HTML] A single amino acid determines lysophospholipid specificity of the S1P1 (EDG1) and LPA1 (EDG2) phospholipid growth factor receptors

D Wang, Z Lorincz, DL Bautista, K Liliom, G Tigyi… - Journal of Biological …, 2001 - ASBMB
… The complex with the best electrostatic interactions selected from the docking procedure
was further refined using molecular dynamics simulations under constant volume at 300 K. …

[HTML][HTML] Photolysis of intracellular caged sphingosine-1-phosphate causes Ca2+ mobilization independently of G-protein-coupled receptors

DM zu Heringdorf, K Liliom, M Schaefer, K Danneberg… - FEBS letters, 2003 - Elsevier
Sphingosine-1-phosphate (S1P), the product of sphingosine kinase, activates several widely
expressed G-protein-coupled receptors (GPCR). S1P might also play a role as second …

Growth factor-like phospholipids generated after corneal injury

K Liliom, Z Guan, JL Tseng… - … of Physiology-Cell …, 1998 - journals.physiology.org
The present study provides evidence that growth factor-like glycerophosphate mediators of
the lysophosphatidic acid (LPA) family are present in the aqueous humor and the lacrimal …

Dual coding in alternative reading frames correlates with intrinsic protein disorder

E Kovacs, P Tompa, K Liliom… - Proceedings of the …, 2010 - National Acad Sciences
Numerous human genes display dual coding within alternatively spliced regions, which give
rise to distinct protein products that include segments translated in more than one reading …

[PDF][PDF] Regulation of the equilibrium between closed and open conformations of annexin A2 by N-terminal phosphorylation and S100A4-binding

…, G Gógl, L Radnai, L Buday, K Koprivanacz, K Liliom… - Structure, 2017 - cell.com
… DCp of unfolding was set to 15 kJ ∙ K-1 ∙ mol-1 in accordance with Cooper who estimated
that the contribution of a residue to DCp is approximately 0.05 kJ ∙ K-1 ∙ mol-1 in a globular …

[HTML][HTML] The phospholipase A1 activity of lysophospholipase AI links platelet activation to LPA production during blood coagulation [S]

…, MD Best, T Sano, T Tsukahara, K Liliom… - Journal of lipid …, 2011 - ASBMB
Platelet activation initiates an upsurge in polyunsaturated (18:2 and 20:4) lysophosphatidic
acid (LPA) production. The biochemical pathway(s) responsible for LPA production during …

Naturally occurring analogs of lysophosphatidic acid elicit different cellular responses through selective activation of multiple receptor subtypes

DJ Fischer, K Liliom, Z Guo, N Nusser, T Virág… - Molecular …, 1998 - ASPET
Lysophosphatidic acid (LPA), plasmalogen-glycerophosphate (alkenyl-GP) and, cyclic-phosphatidic
acid (cyclic-PA) are naturally occurring phospholipid growth factors (PLGFs). PLGFs …