[HTML][HTML] Green tea halts progression of cardiac transthyretin amyloidosis: an observational report

…, C Röcken, EE Wanker, TJ Dengler, K Altland… - Clinical Research in …, 2012 - Springer
… Resting LV function was determined by cine images using a segmented k-space balanced
fast-field-echo sequence (Steady-State-Free-Precession, matrix = 160/256, sense-factor = 2, …

D18G transthyretin is monomeric, aggregation prone, and not detectable in plasma and cerebrospinal fluid: a prescription for central nervous system amyloidosis?

…, RL Wiseman, A Lim, CE Costello, K Altland… - Biochemistry, 2003 - ACS Publications
… Klaus Altland … This molecule binds WT TTR with high affinity; K d1 and K d2 ≈ 3 nM by
isothermal … Klaus Altland - The Skaggs Institute of Chemical Biology and Department of Chemistry…

99mTc-DPD scintigraphy in transthyretin-related familial amyloidotic polyneuropathy

M Puille, K Altland, RP Linke, MK Steen-Müller… - European journal of …, 2002 - Springer
Familial amyloidotic polyneuropathy (FAP) caused by amyloidogenic transthyretin (ATTR)
mutations is the most common form of hereditary amyloidosis. We investigated the diagnostic …

Cardiac amyloidosis: a review and report of a new transthyretin (prealbumin) variant.

A Hesse, K Altland, RP Linke, MR Almeida, MJ Saraiva… - Heart, 1993 - heart.bmj.com
Cardiac amyloidosis is caused by amyloid deposits derived from different human plasma
proteins. It can lead to cardiac conduction disturbances, restrictive cardiomyopathy, and low …

Green tea extract as a treatment for patients with wild-type transthyretin amyloidosis: an observational study

…, M Aurich, SJ Buss, H Steen, K Altland… - Drug Design …, 2015 - Taylor & Francis
Background Causative treatment of patients with wild-type transthyretin amyloid cardiomyopathy
(wtATTR-CM) is lacking. Recent reports indicate the potential use of epigallocatechin-3-…

[HTML][HTML] Structural analysis of human apolipoprotein AI variants. Amino acid substitutions are nonrandomly distributed throughout the apolipoprotein AI primary …

A Von Eckardstein, H Funke, M Walter, K Altland… - Journal of Biological …, 1990 - Elsevier
… Utermann and K. Altland. was limited to residues 103-198 (p < 0.05) or 103-177 (p < 0.025),
stretches that include the first and the last positions of substituted amino acids in this region. …

Skeletal scintigraphy indicates disease severity of cardiac involvement in patients with senile systemic amyloidosis

…, AD Ho, U Haberkorn, TJ Dengler, K Altland… - International journal of …, 2013 - Elsevier
BACKGROUND: Senile systemic amyloidosis (SSA) is a common aging phenomenon in the
elderly population. Nevertheless, pre-mortem diagnosis of SSA is rare. Thus, data on …

Two transthyretin variants (TTR Ala‐49 and TTR Gln‐89) in two Sicilian kindreds with hereditary amyloidosis

…, F Salvi, R Plasmati, CA Tassinari, K Altland… - Human …, 1992 - Wiley Online Library
We report the biochemical and molecular characterization of two new transthyretin (TTR)
variants in two Italian families with hereditary amyloidosis. Both families presented neuropathy …

Transthyretin Leu 68 in a form of cardiac amyloidosis

…, A Hesse, A Steinmetz, B Maisch, K Altland… - Basic research in …, 1991 - Springer
A form of transthyretin (TTR)-related cardiac amyloidosis was previously described in a
German patient. Electrophoretic analysis of plasma TTR showed the presence of an electrically …

Screening and biochemical characterization of transthyretin variants in the Portuguese population

IL Alves, K Altland, MR Almeida, P Winter… - Human …, 1997 - Wiley Online Library
… The procedure is essentially that described by Altland et al. (1987) with the following
modifications. (1) The urea concentration in the gel for hybrid isoelectric focusing was lowered to …