… Interestingly, dotted structure of Mff disperses throughout the MOM in the absence of Drp1
(Otera and Mihara; unpublished results), suggesting that Drp1 affects oligomerization of Mff. …

Conjugated fatty acids have attracted much attention as a novel type of biologically beneficial
functional lipid. Some isomers of conjugated linoleic acid (CLA) reduce carcinogenesis, …

Mitochondria are highly dynamic organelles that continuously change their shape through
frequent fusion, fission and movement throughout the cell, and these dynamics are crucial for …

… Youle, Katsuyoshi Mihara; Mff is an essential factor for mitochondrial recruitment of Drp1
during mitochondrial fission in mammalian cells. J Cell Biol 13 December 2010; 191 (6): 1141–…

… We thank Dr Toshihiko Oka, Dr Noboru Mizushima, Dr Akira Kondo and members of the
Mihara laboratory for productive discussions. We also thank Dr Richard Youle and Dr Atsushi …

To develop a therapy for drug-resistant B-lineage acute lymphoblastic leukemia (ALL), we
transduced T lymphocytes with anti-CD19 chimeric receptors, consisting of an anti-CD19 …

… Katsuyoshi Mihara … -α-tubulin expression plasmid was a generous gift from K. Ohashi
and K. Mizuno, Tohoku University. The cDNA (encoding 705 amino acid residues) of rat Drp1 ( …

… We also thank EI Rugarli, A Bernacchia, and K Sakaki for helpful discussion. This work was
supported by grants from the Ministry of Education, Science, and Culture of Japan, from the …

Background—Tumor necrosis factor-α (TNF-α) and angiotensin II (Ang II) modulate heart
failure in part by provoking the hypertrophic response. Signal transduction pathways of those …

The mammalian homologues of yeast and Drosophila Fzo, mitofusin (Mfn) 1 and 2, are both
essential for mitochondrial fusion and maintenance of mitochondrial morphology. Though …