Polyamine analogues–an update

HM Wallace, K Niiranen - Amino acids, 2007 - Springer
The polyamines are growth factors in both normal and cancer cells. As the intracellular
polyamine content correlates positively with the growth potential of that cell, the idea that …

Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism

…, S Fatrai, E Kansanen, S Koota, K Niiranen… - … and cellular biology, 2007 - Taylor & Francis
… DNA was isolated from WAT of 6-month-old female SSAT and Wt mice by use of proteinase
K and phenol-chloroform-isoamyl alcohol extraction. Quantitative RT-PCRs were performed …

Mice with targeted disruption of spermidine/spermine N1‐acetyltransferase gene maintain nearly normal tissue polyamine homeostasis but show signs of insulin …

K Niiranen, TA Keinänen, E Pirinen… - Journal of cellular …, 2006 - Wiley Online Library
The N 1 ‐acetylation of spermidine or spermine by spermidine/spermine N 1 ‐acetyltransferase
(SSAT) is the ratecontrolling enzymatic step in the polyamine catabolism. We have now …

[HTML][HTML] Potential role of a navigator gene NAV3 in colorectal cancer

…, U Aapola, R Ässämäki, V Häyry, K Niiranen… - British journal of …, 2012 - nature.com
Background: The recently described navigator proteins have a multifaceted role in
cytoskeletal dynamics. We report here on the relevance of one of them, navigator 3 (NAV3), in …

Neuron navigator 3 alterations in nervous system tumors associate with tumor malignancy grade and prognosis

…, S Hussein, S Sarna, K Niiranen… - Genes …, 2013 - Wiley Online Library
Copy number changes or reduced expression of the Neuron navigator 3 (NAV3) gene occurs
in neuroblastomas and malignancies of epithelial or lymphoid origin. To elucidate whether …

[HTML][HTML] Targeted Disruption of Spermidine/SpermineN 1-Acetyltransferase Gene in Mouse Embryonic Stem Cells: EFFECTS ON POLYAMINE HOMEOSTASIS AND …

K Niiranen, M Pietilä, TJ Pirttilä, A Järvinen… - Journal of Biological …, 2002 - ASBMB
We have generated mouse embryonic stem cells with targeted disruption of spermidine/spermineN
1 -acetyltransferase (SSAT) gene. The targeted cells did not contain any inducible …

[HTML][HTML] Mineralogical imaging for characterization of the per geijer apatite iron ores in the Kiruna District, Northern Sweden: a comparative study of mineral liberation …

P Krolop, A Jantschke, S Gilbricht, K Niiranen, T Seifert - Minerals, 2019 - mdpi.com
The Per Geijer iron oxide apatite deposits are important potential future resources for
Luossavaara-Kiirunavaara Aktiebolag (LKAB) which has been continuously mining magnetite/…

[PDF][PDF] The many faces of solitary and multiple erythema migrans

P Eriksson, MT Schroder, K Niiranen… - Acta Dermato …, 2013 - researchportal.helsinki.fi
… (J, K) MEM lesions on the right ankle on a 40-year-old woman. (L) SEM on the back of a
64-year-old woman. The atypical clinical appearance might be a result of a preceding treatment …

Spermine deficiency resulting from targeted disruption of the spermine synthase gene in embryonic stem cells leads to enhanced sensitivity to antiproliferative drugs

VP Korhonen, K Niiranen, M Halmekytö, M Pietilä… - Molecular …, 2001 - ASPET
Polyamines are known to be essential for normal cell growth and differentiation. However,
despite numerous studies, specific cellular functions of polyamines in general and individual …

Process mineralogical assessment of the grinding products of the per geijer iron oxide-apatite deposits

P Krolop, K Niiranen, S Gilbricht… - Mineral Processing and …, 2022 - Taylor & Francis
… Citation2012; Niiranen Citation2015). A series of analytical methods such as optical microscopy
… Böhm, and K. Niiranen. 2014. Comparison of chemical, physical and optical methods to …