Fascinating (and sometimes technologically important) phenomena occur in systems that
have a spatial dimension comparable to that of a fundamental physical, chemical, or biological …

We describe here the development and implementation of a pilot-scale, in vitro, anticancer
drug screen utilizing a panel of 60 human tumor cell lines organized into subpanels …

This essay focuses on whether FEV1 is the best measure of asthma severity in childhood
asthma. For better or worse, FEV1 has become the gold standard lung function measurement …

We have previously described the application of an automated microculture tetrazolium
assay (MTA) involving dimethyl sulfoxide solubilization of cellular-generated 3-(4,5-…

During 1985–1990 the US National Cancer Institute (NCI) phased out its murine leukemia
P388 anticancer drug screening program and developed as the replacement a new in vitro …

Since 1990, the National Cancer Institute (NCI) has screened more than 60,000 compounds
against a panel of 60 human cancer cell lines. The 50-percent growth-inhibitory …

Anthrax lethal toxin, produced by the bacterium Bacillus anthracis, is the major cause of
death in animals infected with anthrax. One component of this toxin, lethal factor (LF), is …

The objective of this study was to develop and investigate an approach to optimally detect,
rank, display, and analyze patterns of differential growth inhibition among cultured cell lines. …

The National Cancer Institute (NCI) is implementing a large-scale in vitro drug-screening
program that requires a very efficient automated assay of drug effects on tumor cell viability or …

The present study was designed to explore the activity of platinum compounds in cisplatinresistant
cell lines, the unselected cell lines of the National Cancer Institute's Anticancer Drug …