… clearance that is equivalent to V·k e . Average values for f,V, k e , and CL/f for a number of
agents in old and young adults have been published previously (Turnheim, 1998). It should be …

… clearance that is equivalent to V·k e . Average values for f, V, k e , and CL/f for a number of
agents in old and young adults have been published previously (Turnheim, 1998). It should …

Pharmacotherapy in the elderly requires an understanding of the age-dependent changes
in function and composition of the body. Aging is characterised by a progressive loss of …

… k e and t max are known, k a can be calculated from k a = k e · ξ. Because Eq. 1 is transcendental
and cannot be solved for ξ, values for ξ as a function of k … increase in k a with k e being …

Background Previous studies suggest that caudal administration of ketamine cause effective
analgesia. The purpose of the current study was to compare the clinical effectiveness and …

Purpose The transversus abdominis plane (TAP) block is a regional anesthetic technique
used for pain control following abdominal surgical procedures. While a minimum of systemic …

… On the basis of measurements of radionuclide fluxes or amiloride-inhibitable transapical
current in the presence of Na+ or K+ gradients, a Na+-K+ selectivity of lOO-1,000 was reported …

… In 7 men >70 years, the tl;' of indomethacin was reported to be 1.7h (corresponding to a
ke of 0.40 h-I ) and 1.5h in 7 men <50 years (ke = 0.45 h- I ). These tl;' values are short compared …

Ageing is associated with a decline in drug elimination; hence, using the same doses as in
younger adults may result in higher plasma drug concentrations and toxicity. Two …

A rapid and low-cost assay for simultaneous vigabatrin (VGA) and gabapentin (GBP)
determination is described that can be performed with simple HPLC instrumentation. The method …