Gene expression profiling in the leukemic stem cell-enriched CD34+ fraction identifies target genes that predict prognosis in normal karyotype AML

…, A Mulder, E van den Berg, PM Kluin, K Van Der Weide… - Leukemia, 2011 - nature.com
K van der Weide … protein) was shown to selectively bind and dephosphorylate the
transcriptional regulator heterogeneous nuclear ribonucleoprotein K by targeting … K van der Weide

The influence of the CYP3A4* 22 polymorphism and CYP2D6 polymorphisms on serum concentrations of aripiprazole, haloperidol, pimozide, and risperidone in …

K van der Weide, J van der Weide - Journal of clinical …, 2015 - journals.lww.com
Methods Eight hundred thirty-four adult patients were included in this study, of whom 130
used aripiprazole, 312 used haloperidol, 86 used pimozide, and 396 used risperidone. Serum …

Site-specific inhibition of glomerulonephritis progression by targeted delivery of dexamethasone to glomerular endothelium

…, P Heeringa, K van der Weide, H van Goor… - Molecular …, 2007 - ASPET
Glomerulonephritis represents a group of renal diseases with glomerular inflammation as a
common pathologic finding. Because of the underlying immunologic character of these …

The influence of the CYP3A4* 22 polymorphism on serum concentration of quetiapine in psychiatric patients

K van der Weide, J van der Weide - Journal of clinical …, 2014 - journals.lww.com
Background Besides dietary, hormonal, or pathological factors, mutations in cytochrome
P450 enzymes are thought to be responsible for the interindividual differences in serum …

Genetic risk factors for clozapine-induced neutropenia and agranulocytosis in a Dutch psychiatric population

K Van Der Weide, H Loovers, K Pondman… - The …, 2017 - nature.com
Prescription of clozapine is complicated by the occurrence of clozapine-induced reduction
of neutrophils. The aim of this study was to identify genetic risk factors in a population of 310 …

[HTML][HTML] HLA-DQB1 6672G> C (rs113332494) is associated with clozapine-induced neutropenia and agranulocytosis in individuals of European ancestry

…, JP Bogers, J van der Weide, K van der Weide… - Translational …, 2021 - nature.com
The atypical antipsychotic clozapine is the only effective medication for treatment-resistant
schizophrenia. However, it can also induce serious adverse drug reactions, including …

[HTML][HTML] Clinical stance on response initiation in autistic adults: co-creating an integrative approach based on theory and lived experiences to act from language, via …

…, B de Graaff, J Landsman, K van der Weide… - Frontiers in …, 2023 - frontiersin.org
Getting ‘stuck’, literally and figuratively, is a common experience for autistic people. Literally ‘stuck’
means exhibiting limited response initiation due to immobility with tense muscles and …

Combining Simvastatin with the Farnesyltransferase Inhibitor Tipifarnib Results in an Enhanced Cytotoxic Effect in a Subset of Primary CD34+ Acute Myeloid …

K van der Weide, SD de Jonge-Peeters, F Kuipers… - Clinical Cancer …, 2009 - AACR
… Karen van der Weide … Karen van der Weide, Susan DPWM de Jonge-Peeters, Folkert Kuipers,
Elisabeth … This is consistent with the idea that K-Ras and N-Ras can be both farnesylated …

Heterogeneity in simvastatin-induced cytotoxicity in AML is caused by differences in Ras-isoprenylation

K van der Weide, PM Korthuis, F Kuipers, EGE de Vries… - Leukemia, 2012 - nature.com
… 4.van der Weide K, Jonge-Peeters SD, Kuipers F, de Vries EG, Vellenga E . Combining …
K- and N-Ras are geranylgeranylated in cells treated with farnesyl protein … K van der Weide

Establishing the cause of anemia in a premature newborn infant

G den Besten, K van der Weide… - Laboratory …, 2018 - academic.oup.com
The three major causes of anemia in neonates are blood loss, decreased red blood cell
production, and increased degradation of erythrocytes. Establishing the cause of anemia in a …