Nitric oxide synthase in cardiac sarcoplasmic reticulum
KY Xu, DL Huso, TM Dawson… - Proceedings of the …, 1999 - National Acad Sciences
NO ⋅ is a free radical that modulates heart function and metabolism. We report that a
neuronal-type NO synthase (NOS) is located on cardiac sarcoplasmic reticulum (SR) membrane …
neuronal-type NO synthase (NOS) is located on cardiac sarcoplasmic reticulum (SR) membrane …
Hydroxyl Radical Inhibits Sarcoplasmic Reticulum Ca2+-ATPase Function by Direct Attack on the ATP Binding Site
KY Xu, JL Zweier, LC Becker - Circulation research, 1997 - Am Heart Assoc
Oxygen-derived free radicals have been reported to damage the sarcoplasmic reticulum (SR)
Ca 2+ -ATPase, potentially contributing to cellular Ca 2+ overload and myocardial damage …
Ca 2+ -ATPase, potentially contributing to cellular Ca 2+ overload and myocardial damage …
Functional Coupling Between Glycolysis and Sarcoplasmic Reticulum Ca2+ Transport
KY Xu, JL Zweier, LC Becker - Circulation research, 1995 - Am Heart Assoc
To investigate whether the energy derived from glycolysis is functionally coupled to Ca 2+
active transport in sarcoplasmic reticulum (SR), we determined whether glycolytic enzymes …
active transport in sarcoplasmic reticulum (SR), we determined whether glycolytic enzymes …
Ultrastructural localization of glycolytic enzymes on sarcoplasmic reticulum vesicles
KY Xu, LC Becker - Journal of Histochemistry & …, 1998 - journals.sagepub.com
We have previously obtained indirect evidence that sarcoplasmic reticulum (SR) vesicles
from cardiac and skeletal muscle contain the complete chain of glycolytic enzymes from …
from cardiac and skeletal muscle contain the complete chain of glycolytic enzymes from …
Activation of (Na++ K+)-ATPase
KY Xu - Biochemical and biophysical research communications, 2005 - Elsevier
Enzymes catalyze essential chemical reactions needed for living processes. (Na + +K + )-ATPase
(NKA) is one of the key enzymes that control intracellular ion homeostasis and …
(NKA) is one of the key enzymes that control intracellular ion homeostasis and …
Arcuate Na+,K+-ATPase senses systemic energy states and regulates feeding behavior through glucose-inhibited neurons
H Kurita, KY Xu, Y Maejima, M Nakata… - American Journal …, 2015 - journals.physiology.org
Feeding is regulated by perception in the hypothalamus, particularly the first-order arcuate
nucleus (ARC) neurons, of the body's energy state. However, the cellular device for …
nucleus (ARC) neurons, of the body's energy state. However, the cellular device for …
[HTML][HTML] Nitric oxide protects cardiac sarcolemmal membrane enzyme function and ion active transport against ischemia-induced inactivation
KY Xu, SP Kuppusamy, JQ Wang, H Li, H Cui… - Journal of Biological …, 2003 - ASBMB
Nitric oxide (NO . ) generated from nitric oxide synthase (NOS) isoforms bound to cellular
membranes may serve to modulate oxidative stresses in cardiac muscle and thereby regulate …
membranes may serve to modulate oxidative stresses in cardiac muscle and thereby regulate …
Activation of (Na++ K+)-ATPase induces positive inotropy in intact mouse heart in vivo
KY Xu, E Takimoto, NS Fedarko - Biochemical and biophysical research …, 2006 - Elsevier
OBJECTIVE: We have recently identified an activation site on (Na + +K + )-ATPase and found
that binding of antibody SSA412 to this specific site of the enzyme markedly augments (Na …
that binding of antibody SSA412 to this specific site of the enzyme markedly augments (Na …
Lack of nitric oxide synthase depresses ion transporting enzyme function in cardiac muscle
Nitric oxide (NO ) is produced endogenously from NOS isoforms bound to sarcolemmal (SL)
and sarcoplasmic reticulum (SR) membranes. To investigate whether locally generated NO …
and sarcoplasmic reticulum (SR) membranes. To investigate whether locally generated NO …
Transcription factor competition at the γ-globin promoters controls hemoglobin switching
… box is occupied by the activator NF-Y. BCL11A competes with NF-Y binding through steric
hindrance to initiate repression. Occupancy of NF-Y is rapidly established following BCL11A …
hindrance to initiate repression. Occupancy of NF-Y is rapidly established following BCL11A …