Cellular efflux of auxin catalyzed by the Arabidopsis MDR/PGP transporter AtPGP1
…, WA Peer, A Bailly, EL Richards, KFK Ejendal… - The Plant …, 2005 - Wiley Online Library
Directional transport of the phytohormone auxin is required for the establishment and
maintenance of plant polarity, but the underlying molecular mechanisms have not been fully …
maintenance of plant polarity, but the underlying molecular mechanisms have not been fully …
[HTML][HTML] Microfluidic rapid and autonomous analytical device (microRAAD) to detect HIV from whole blood samples
While identifying acute HIV infection is critical to providing prompt treatment to HIV-positive
individuals and preventing transmission, existing laboratory-based testing methods are too …
individuals and preventing transmission, existing laboratory-based testing methods are too …
Substrate overlap between Mrp4 and Abcg2/Bcrp affects purine analogue drug cytotoxicity and tissue distribution
…, M Adachi, CF Stewart, D Sun, M Leggas, KFK Ejendal… - Cancer research, 2007 - AACR
The use of probe substrates and combinations of ATP-binding cassette (ABC) transporter
knockout (KO) animals may facilitate the identification of common substrates between …
knockout (KO) animals may facilitate the identification of common substrates between …
[HTML][HTML] A “Genome-to-Lead” Approach for Insecticide Discovery: Pharmacological Characterization and Screening of Aedes aegypti D1-like Dopamine Receptors
JM Meyer, KFK Ejendal, LV Avramova… - PLoS neglected …, 2012 - journals.plos.org
Background Many neglected tropical infectious diseases affecting humans are transmitted
by arthropods such as mosquitoes and ticks. New mode-of-action chemistries are urgently …
by arthropods such as mosquitoes and ticks. New mode-of-action chemistries are urgently …
The nature of amino acid 482 of human ABCG2 affects substrate transport and ATP hydrolysis but not substrate binding
KFK Ejendal, NK Diop, LC Schweiger… - Protein …, 2006 - Wiley Online Library
… Karin FK Ejendal … Karin FK Ejendal … prazosin, and the R482 wild-type protein, which
only transports Bodipy FL prazosin to a low extent, are labeled with [ 125 I]IAAP. This finding is …
only transports Bodipy FL prazosin to a low extent, are labeled with [ 125 I]IAAP. This finding is …
[HTML][HTML] Dopamine Receptor Antagonists as New Mode-of-Action Insecticide Leads for Control of Aedes and Culex Mosquito Vectors
AB Nuss, KFK Ejendal, TB Doyle… - PLoS neglected …, 2015 - journals.plos.org
Background New mode-of-action insecticides are sought to provide continued control of
pesticide resistant arthropod vectors of neglected tropical diseases (NTDs). We previously …
pesticide resistant arthropod vectors of neglected tropical diseases (NTDs). We previously …
Fluorescent protein complementation assays: new tools to study G protein-coupled receptor oligomerization and GPCR-mediated signaling
G protein-coupled receptor (GPCR) signaling is mediated by protein–protein interactions at
multiple levels. The characterization of the corresponding protein complexes is therefore …
multiple levels. The characterization of the corresponding protein complexes is therefore …
Differential sensitivities of the human ATP-binding cassette transporters ABCG2 and P-glycoprotein to cyclosporin A
KFK Ejendal, CA Hrycyna - Molecular pharmacology, 2005 - ASPET
Several ATP-binding cassette (ABC) transporters can confer multidrug resistance to cancer
cells by functioning as energy-dependent efflux pumps. The half-transporter ABCG2 and the …
cells by functioning as energy-dependent efflux pumps. The half-transporter ABCG2 and the …
Human cord blood-derived mast cells are activated by the Nod1 agonist M-TriDAP to release pro-inflammatory cytokines and chemokines
M Enoksson, KFK Ejendal, S McAlpine… - Journal of innate …, 2011 - karger.com
Mast cells are among the first cells of our immune system to encounter exogenous danger.
Intracellular receptors such as nucleotide-binding oligomerization domain (Nod) play an …
Intracellular receptors such as nucleotide-binding oligomerization domain (Nod) play an …
Re-invigorating the insecticide discovery pipeline for vector control: GPCRs as targets for the identification of next gen insecticides
G protein-coupled receptors (GPCRs) comprise a large family of membrane-bound molecules
that mediate critical physiological roles in both vertebrates and invertebrates. GPCRs are …
that mediate critical physiological roles in both vertebrates and invertebrates. GPCRs are …