Recombinant human activated protein C reduces human endotoxin-induced pulmonary inflammation via inhibition of neutrophil chemotaxis
…, J O'Brien, M Gruber, S Zarini, RC Murphy, K Kuhn… - Blood, 2004 - ashpublications.org
Recombinant human activated protein C (rhAPC) is a natural anticoagulant with potentially
important anti-inflammatory properties. In humans with severe sepsis, rhAPC treatment …
important anti-inflammatory properties. In humans with severe sepsis, rhAPC treatment …
The primary structure of hen ovotransferrin
…, IB Kingston, AG Wilkins, KA Kuhn - European journal of …, 1982 - Wiley Online Library
Peptide sequences obtained from hen ovotransferrin are compared with the complete
amino acid sequence of the protein deduced from a cDNA sequence (Jeltsch and Chambon, …
amino acid sequence of the protein deduced from a cDNA sequence (Jeltsch and Chambon, …
Phosphoinositide 3-kinase and Akt occupy central roles in inflammatory responses of Toll-like receptor 2-stimulated neutrophils
…, JS Park, JY Kim, Q He, D Richter, K Kuhn… - The Journal of …, 2004 - journals.aai.org
Neutrophils are critical initiators and effectors of the innate immune system and express Toll-like
receptor 2 (TLR2) and TLR4. Although signaling through pathways involving …
receptor 2 (TLR2) and TLR4. Although signaling through pathways involving …
Urokinase-type plasminogen activator potentiates lipopolysaccharide-induced neutrophil activation
E Abraham, MR Gyetko, K Kuhn, J Arcaroli… - The Journal of …, 2003 - journals.aai.org
Urokinase plasminogen activator (uPA) is a serine protease that catalyzes the conversion of
plasminogen to plasmin. Although increased circulating levels of uPA are present in …
plasminogen to plasmin. Although increased circulating levels of uPA are present in …
Downregulation of Dlx5 and Dlx6 expression by Hand2 is essential for initiation of tongue morphogenesis
F Barron, C Woods, K Kuhn, J Bishop… - …, 2011 - journals.biologists.com
Lower jaw development is a complex process in which multiple signaling cascades establish
a proximal-distal organization. These cascades are regulated both spatially and temporally …
a proximal-distal organization. These cascades are regulated both spatially and temporally …
Pathogenesis of human metapneumovirus lung infection in BALB/c mice and cotton rats
ME Hamelin, K Yim, KH Kuhn, RP Cragin… - Journal of …, 2005 - Am Soc Microbiol
Human metapneumovirus (hMPV) is a newly described member of the Paramyxoviridae
family causing acute respiratory tract infections, especially in young children. We studied the …
family causing acute respiratory tract infections, especially in young children. We studied the …
Antitumorigenic effects of peroxisome proliferator-activated receptor-γ in non-small-cell lung cancer cells are mediated by suppression of cyclooxygenase-2 via …
…, AM Meyer, V Van Putten, H Li, K Kuhn… - Molecular …, 2008 - ASPET
Pharmacological activators of peroxisome proliferator-activated receptor-γ (PPARγ) inhibit
growth of non-small-cell lung cancer (NSCLC) cell lines in vitro and in xenograft models. …
growth of non-small-cell lung cancer (NSCLC) cell lines in vitro and in xenograft models. …
Age-related differences in pulmonary cytokine response to respiratory syncytial virus infection: modulation by anti-inflammatory and antiviral treatment
MS Boukhvalova, KC Yim, KH Kuhn… - The Journal of …, 2007 - academic.oup.com
Background. Respiratory syncytial virus (RSV) is the major cause of severe lower respiratory
tract infection in infants and young children. Recently, RSV has also been recognized as a …
tract infection in infants and young children. Recently, RSV has also been recognized as a …
[HTML][HTML] A randomized clinical trial demonstrating cell type specific effects of hyperlipidemia and hyperinsulinemia on pituitary function
R McDonald, K Kuhn, TB Nguyen, A Tannous… - Plos one, 2022 - journals.plos.org
Introduction Obesity is characterized by elevated lipids, insulin resistance and relative
hypogonadotropic hypogonadism, reducing fertility and increasing risk of pregnancy …
hypogonadotropic hypogonadism, reducing fertility and increasing risk of pregnancy …
Modulation of bone marrow-derived neutrophil signaling by H2O2: disparate effects on kinases, NF-κB, and cytokine expression
…, D Richter, S Mitra, J Arcaroli, K Kuhn… - … of Physiology-Cell …, 2004 - journals.physiology.org
Reactive oxygen species (ROS), including hydrogen peroxide (H 2 O 2 ), are generated in
increased amounts in pathological, biological processes and can play a role in signal …
increased amounts in pathological, biological processes and can play a role in signal …