Exploring the structure–activity relationship and mechanism of a chromene scaffold (CXL series) for its selective antiproliferative activity toward multidrug-resistant …
T Bian, K Chandagirikoppal Vijendra… - Journal of medicinal …, 2018 - ACS Publications
Multidrug resistance (MDR) is one major barrier in cancer management, which urges for
new drugs to help treat MDR malignancies and elucidate MDR mechanisms. A series of …
new drugs to help treat MDR malignancies and elucidate MDR mechanisms. A series of …
CXL146, a novel 4H-chromene derivative, targets GRP78 to selectively eliminate multidrug-resistant cancer cells
The 78-kDa glucose-regulated protein (GRP78), an endoplasmic reticulum (ER) chaperone,
is a master regulator of the ER stress. A number of studies revealed that high levels of …
is a master regulator of the ER stress. A number of studies revealed that high levels of …
Correction to “CXL146, a Novel 4H-Chromene Derivative, Targets GRP78 to Selectively Eliminate Multidrug-Resistant Cancer Cells”
… In the above article [Bian T, Tagmount A, Vulpe C, Vijendra KC, and Xing C (2020) Mol
Pharmacol 97:402-408; DOI: https://doi.org/10.1124/mol.119.118745], Amin Sobh was omitted …
Pharmacol 97:402-408; DOI: https://doi.org/10.1124/mol.119.118745], Amin Sobh was omitted …