Role of estrogen replacement therapy in memory enhancement and the prevention of neuronal loss associated with Alzheimer's disease

PS Green, KE Gridley, NEC de Fiebre - The American journal of medicine, 1997 - Elsevier
Recent evidence supports a role for estrogens in both normal neural development and
neuronal maintenance throughout life. Women spend 25–33% of their life in an estrogen-…

Estradiol protects against β-amyloid (25–35)-induced toxicity in SK-N-SH human neuroblastoma cells

PS Green, KE Gridley, JW Simpkins - Neuroscience letters, 1996 - Elsevier
Estrogen-replacement therapy has been associated with a reduced incidence of Alzheimer's
disease (AD) and improved cognition in several small open clinical trials. We assessed the …

Low concentrations of estradiol reduce β-amyloid (25–35)-induced toxicity, lipid peroxidation and glucose utilization in human SK-N-SH neuroblastoma cells

KE Gridley, PS Green, JW Simpkins - Brain research, 1997 - Elsevier
The present studies were undertaken to determine the role of physiologically relevant
concentrations of estrogens on amyloid-induced changes in cell viability, metabolic demands, and …

A novel, synergistic interaction between 17 β-estradiol and glutathione in the protection of neurons against β-amyloid 25–35-induced toxicity in vitro

KE Gridley, PS Green, JW Simpkins - Molecular pharmacology, 1998 - ASPET
The present studies were undertaken to investigate the possibility of an interaction between
17 β-estradiol (E2) and glutathione in protecting cells against the presence of β-amyloid 25–…

Biological activity of 17β-estradiol-3-sulfate in ovine fetal plasma and uptake in fetal brain

CE Wood, KE Gridley, M Keller-Wood - Endocrinology, 2003 - academic.oup.com
In sheep, the fetal hypothalamus-pituitary-adrenal axis plays a central role in the initiation of
parturition. We have reported that estradiol dramatically increases the activity of the fetal …

Neuroprotective effects of estrogens

JW Simpkins, PS Green, KE Gridley, J Shi… - Biology of …, 2000 - Springer
Postmenopausal estrogen replacement therapy (ERT) is associated with numerous overall
health benefits, including reduced risk of osteoporosis and a decrease in mortality (1). Of …

Cellular localization of thromboxane synthase in ovine spinal cord and hindbrain

D Husted, J Upshaw, KE Gridley, CE Wood - Brain research, 2003 - Elsevier
We and others have demonstrated that endogenously-produced prostanoids modify the
function of the hypothalamus–pituitary–adrenal (HPA) axis. We have demonstrated that …

Etiologies and predictors of diagnosis in nonresponsive celiac disease

…, B Hyett, E Kelly, D Schuppan, CP Kelly - Clinical …, 2007 - Elsevier
Background & Aims: Nonresponsive celiac disease (NRCD) is a common problem affecting
from 7% to 30% of celiac patients. Because NRCD comprises varied and potentially morbid …

Induction of immunoreactive prostaglandin H synthases 1 and 2 and fos in response to cerebral hypoperfusion in late-gestation fetal sheep

H Tong, KE Gridley, CE Wood - The Journal of the Society for Gynecologic …, 2002 - Springer
Objective The goal of the present study was to localize and quantify immunoreactive protaglandin
H synthase 1 (PGHS-1), PGHS-2, and Fos expression by immunohistochemistry in the …

Standardizing perioperative medications to be used in an enhanced recovery after surgery program is feasible in percutaneous nephrolithotomy patients

CBL Girgiss, JH Berger, TT Chen, EM Kelly… - Journal of …, 2022 - liebertpub.com
… Our approach to pain management was similar to that of Gridley and colleagues, Large
and colleagues, and Sobel and colleagues, 5,19,20 who all used multimodal analgesic …