User profiles for Kevin P. M. Currie
Kevin PM CurrieCooper Medical School of Rowan University Verified email at rowan.edu Cited by 2067 |
[HTML][HTML] Regulation of CaV2 calcium channels by G protein coupled receptors
GW Zamponi, KPM Currie - Biochimica et Biophysica Acta (BBA) …, 2013 - Elsevier
Voltage gated calcium channels (Ca 2+ channels) are key mediators of depolarization
induced calcium influx into excitable cells, and thereby play pivotal roles in a wide array of …
induced calcium influx into excitable cells, and thereby play pivotal roles in a wide array of …
G protein inhibition of CaV2 calcium channels
KPM Currie - Channels, 2010 - Taylor & Francis
Voltage-gated Ca 2+ channels translate the electrical inputs of excitable cells into biochemical
outputs by controlling influx of the ubiquitous second messenger Ca 2+ . As such the …
outputs by controlling influx of the ubiquitous second messenger Ca 2+ . As such the …
Serotonin and serotonin transporters in the adrenal medulla: a potential hub for modulation of the sympathetic stress response
…, MB Bauer, RD Blakely, KPM Currie - ACS chemical …, 2017 - ACS Publications
Serotonin (5-HT) is an important neurotransmitter in the central nervous system where it
modulates circuits involved in mood, cognition, movement, arousal, and autonomic function. The …
modulates circuits involved in mood, cognition, movement, arousal, and autonomic function. The …
Calpains play a role in insulin secretion and action
…, YP Zhou, K Otani, PA Hansen, KPM Currie… - Diabetes, 2001 - Am Diabetes Assoc
Studies of the genetic basis of type 2 diabetes suggest that variation in the calpain-10 gene
affects susceptibility to this common disorder, raising the possibility that calpain-sensitive …
affects susceptibility to this common disorder, raising the possibility that calpain-sensitive …
Comparison of N-and P/Q-type voltage-gated calcium channel current inhibition
KPM Currie, AP Fox - Journal of Neuroscience, 1997 - Soc Neuroscience
Activation of N- and P/Q-type voltage-gated calcium channels triggers neurotransmitter
release at central and peripheral synapses. These channels are targets for regulatory …
release at central and peripheral synapses. These channels are targets for regulatory …
The role of dynamic palmitoylation in Ca2+ channel inactivation
JH Hurley, AL Cahill, KPM Currie… - Proceedings of the …, 2000 - National Acad Sciences
N- and P/Q-type Ca 2+ channels regulate a number of critical physiological processes including
synaptic transmission and hormone secretion. These Ca 2+ channels are multisubunit …
synaptic transmission and hormone secretion. These Ca 2+ channels are multisubunit …
[HTML][HTML] ATP serves as a negative feedback inhibitor of voltage-gated Ca2+ channel currents in cultured bovine adrenal chromaffin cells
KPM Currie, AP Fox - Neuron, 1996 - cell.com
… Kevin PM Currie Kevin PM Currie … The ATP exerts its actions through P 2Y purinoceptors
and inhibits both N- and P/Q-type Ca 2+ channels in a voltage-dependent manner but with …
and inhibits both N- and P/Q-type Ca 2+ channels in a voltage-dependent manner but with …
Differential facilitation of N‐and P/Q‐type calcium channels during trains of action potential‐like waveforms
KPM Currie, AP Fox - The Journal of physiology, 2002 - Wiley Online Library
Inhibition of presynaptic voltage‐gated calcium channels by direct G‐protein βγ subunit
binding is a widespread mechanism that regulates neurotransmitter release. Voltage‐dependent …
binding is a widespread mechanism that regulates neurotransmitter release. Voltage‐dependent …
[HTML][HTML] Gβγ directly modulates vesicle fusion by competing with synaptotagmin for binding to neuronal SNARE proteins embedded in membranes
…, JA Gilbert, O Cruz-Rodriguez, KPM Currie… - Journal of Biological …, 2017 - ASBMB
G i/o -coupled G protein-coupled receptors can inhibit neurotransmitter release at synapses
via multiple mechanisms. In addition to Gβγ-mediated modulation of voltage-gated calcium …
via multiple mechanisms. In addition to Gβγ-mediated modulation of voltage-gated calcium …
Aspects of calcium-activated chloride currents: a neuronal perspective
…, KG Sutton, A Griffin, SR Stapleton, KPM Currie - Pharmacology & …, 1995 - Elsevier
Ca 2+ -activated Cl − channels are expressed in a variety of cell types, including central and
peripheral neurones. These channels are activated by a rise in intracellular Ca 2+ close to …
peripheral neurones. These channels are activated by a rise in intracellular Ca 2+ close to …