(H+, K+)-ATPase inhibiting 2-[(2-pyridylmethyl) sulfinyl] benzimidazoles. 4. A novel series of dimethoxypyridyl-substituted inhibitors with enhanced selectivity. The …
…, H Schaefer, G Rainer, V Figala, K Klemm - Journal of medicinal …, 1992 - ACS Publications
[(Pyridylmethyl) sulfinyl] benzimidazoles 1 (PSBs) are a class of highly potentantisecretory (H+,
K+)-ATPase inhibitors which need to be activated by acid to formtheir active principle, the …
K+)-ATPase inhibitors which need to be activated by acid to formtheir active principle, the …
Primary structure differences of human surfactant-associated proteins isolated from normal and proteinosis lung
…, E Hannappel, J Maaßen, B Landis, K Klemm… - … et Biophysica Acta (BBA …, 1992 - Elsevier
The primary structures of human pulmonary surfactant-associated proteins SP-A, SP-B and
SP-C isolated from lung lavage of patients with alveolar proteinosis exhibit significant …
SP-C isolated from lung lavage of patients with alveolar proteinosis exhibit significant …
Characterization of the dexniguldipine binding site in the multidrug resistance-related transport protein P-glycoprotein by photoaffinity labeling and mass spectrometry
C Borchers, R Boer, K Klemm, V Figala… - Molecular …, 2002 - ASPET
Human P-glycoprotein (P-gp), an integral membrane transport protein, is responsible for the
efflux of various drugs, including cytostatics from cancer cells leading to multidrug resistance…
efflux of various drugs, including cytostatics from cancer cells leading to multidrug resistance…
(H+-K+)-ATPase inhibiting 2-[(2-pyridylmethyl) sulfinyl] benzimidazoles. 2. The reaction cascade induced by treatment with acids. Formation of 5H-pyrido [1', 2': 4, 5][1 …
…, U Krueger, E Sturm, V Figala, K Klemm… - The Journal of …, 1987 - ACS Publications
The elucidation of the acid catalyzed chemical transformations involved in the inhibition of
the gastric (H+-K+)-ATPase by 2-[(2-pyridylmethyl) sulfinyl] benzimidazoles 1, a new class of …
the gastric (H+-K+)-ATPase by 2-[(2-pyridylmethyl) sulfinyl] benzimidazoles 1, a new class of …
(H+-K+)-ATPase inhibiting 2-[(2-pyridylmethyl) sulfinyl] benzimidazoles. 1. Their reaction with thiols under acidic conditions. Disulfide containing 2 …
…, J Senn-Bilfinger, V Figala, K Klemm… - The Journal of …, 1987 - ACS Publications
… Ernst Sturm,* Uwe Krüger, Jórg Senn-Bilfinger,Volker Figala, Kurt Klemm, Bernhard Kohl,
Georg Rainer, and Hartmann Schaefer … (13) Figala, V.; Klemm, K.; Kohl, B.; Krüger, U.; …
Georg Rainer, and Hartmann Schaefer … (13) Figala, V.; Klemm, K.; Kohl, B.; Krüger, U.; …
(H+-K+)-ATPase inhibiting 2-[(2-pyridylmethyl) sulfinyl] benzimidazoles. 3. Evidence for the involvement of a sulfenic acid in their reactions
…, E Sturm, V Figala, K Klemm… - The Journal of …, 1990 - ACS Publications
The (H+-K+)-ATPase inhibiting sulfoxides la, b undergo acid-induced transformationsinto
the cyclicsulfenamides 2a, b via the putative sulfenic acids 4a, b. At high concentrations …
the cyclicsulfenamides 2a, b via the putative sulfenic acids 4a, b. At high concentrations …
B9209-005, an azido derivative of the chemosensitizer dexniguldipine-HCl, photolabels P-glycoprotein.
C Borchers, WR Ulrich, K Klemm, W Ise, V Gekeler… - Molecular …, 1995 - ASPET
P-glycoprotein is an energy-dependent drug extrusion pump for a variety of anticancer drugs
and is involved in the development of multidrug resistance in cancer. Dexniguldipine-HCl is …
and is involved in the development of multidrug resistance in cancer. Dexniguldipine-HCl is …
Formamid‐Reaktionen, XIV. Reaktionen von Säureamid‐Acylhalogenid‐Addukten: Darstellung substituierter Amidine und Amidrazone
H Bredereck, R Gompper, K Klemm… - Chemische …, 1959 - Wiley Online Library
Die Struktur des kristallin erhaltenen Dimethylformamid‐Phosphoroxychlorid‐Adduktes wird
erörtert. NN‐Disubstituierte Amide geben mit Phosphoroxychlorid und Aminen NNN′‐…
erörtert. NN‐Disubstituierte Amide geben mit Phosphoroxychlorid und Aminen NNN′‐…
A unique approach to preventing back pain in the dental office
GJ Books, K Klemm - Work, 2012 - content.iospress.com
Back pain has been reported by a majority of dental practitioners for decades. Efforts to relieve
pain have focused on postural modification, exercise, and equipment designed to facilitate…
pain have focused on postural modification, exercise, and equipment designed to facilitate…
Formamid‐Reaktionen, XII. Alkylierungs‐und Acylierungsreaktionen an Formamid: Tris‐formylamino‐methan
…, R Gompper, H Rempfer, K Klemm… - Chemische …, 1959 - Wiley Online Library
Die Einwirkung von Alkylierungsmitteln auf Formamid (2 Moll.) liefert Formamidin. Mit einem
Überschuß von Formamid (5–10 Moll.) entsteht Tris‐formylamino‐methan. Die Verbindung …
Überschuß von Formamid (5–10 Moll.) entsteht Tris‐formylamino‐methan. Die Verbindung …