The anticancer ruthenium complex KP1019 induces DNA damage, leading to cell cycle delay and cell death in Saccharomyces cerevisiae

…, AP Strehle, RL Miller, SH Gammons, KJ Hoffman… - Molecular …, 2013 - ASPET
The anticancer ruthenium complex trans-[tetrachlorobis(1H-indazole)ruthenate(III)], otherwise
known as KP1019, has previously been shown to inhibit proliferation of ovarian tumor cells…

Protective and antifungal properties of Nanodisk‐Amphotericin B over commercially available Amphotericin B

DY Cho, KJ Hoffman, GS Gill, DJ Lim… - World Journal of …, 2017 - Wiley Online Library
Objective Amphotericin B (AMB), a potent antifungal agent, has been employed as topical
and systemic therapy for sinonasal fungal infections. A novel formulation of nanodisc (ND) …

Ontogeny of otolith formation in two demersal estuarine reef fishes

KJ Hoffman, JM Harding - Journal of North Carolina …, 2018 - meridian.allenpress.com
Planktonic reef fish larvae locate and orient to reefs during settlement. Consequently,
metamorphosis occurs in appropriate juvenile and/or adult habitats. Larval fish use otoliths for …

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

…, T Hoffman, V Agarwal, PG Williams, J Dai… - Nature …, 2016 - nature.com
The potential of the diverse chemistries present in natural products (NP) for biotechnology
and medicine remains untapped because NP databases are not searchable with raw data …

Mars Oxygen ISRU Experiment (MOXIE)—preparing for human Mars exploration

JA Hoffman, MH Hecht, D Rapp, JJ Hartvigsen… - Science …, 2022 - science.org
MOXIE [Mars Oxygen In Situ Resource Utilization (ISRU) Experiment] is the first demonstration
of ISRU on another planet, producing oxygen by solid oxide electrolysis of carbon dioxide …

[PDF][PDF] Identity crisis of an athlete/student

KJ Hoffman - 2016 - fisherpub.sjf.edu
The purpose of this study was to understand the self-identity of an athlete and how the label
of being an athlete impacted decisions and behaviors of a person. In previous research …

Optimizing anticoagulation management through the use of a hospital engagement network metric for inpatient anticoagulant-associated hemorrhage

JL Hoffman, NJ Aneese, KJ Schmidt… - Annals of …, 2015 - journals.sagepub.com
Background: The University HealthSystem Consortium (UHC), a national hospital engagement
network (HEN), establishes health-system metrics to assess and improve quality of care. …

Bioavailability and efficiency of rutin as an antioxidant: a human supplementation study

…, SJ Duthie, DC Hinselwood, JAM Kyle… - European Journal of …, 2000 - nature.com
… Echinone was kindly donated by F Hoffman La Roche AG, Basle, Switzerland. Genesis C18.
4 mm (150 64.6mm id) and Nucleosil ODS 5 mm (25064.6mm id) columns were purchased …

[PDF][PDF] Proteogenomic and metabolomic characterization of human glioblastoma

LB Wang, A Karpova, MA Gritsenko, JE Kyle, S Cao… - Cancer cell, 2021 - cell.com
Glioblastoma (GBM) is the most aggressive nervous system cancer. Understanding its
molecular pathogenesis is crucial to improving diagnosis and treatment. Integrated analysis of …

[PDF][PDF] MARRVEL: integration of human and model organism genetic resources to facilitate functional annotation of the human genome

…, DM Krasnewich, EL Krieg, JB Krier, JE Kyle… - The American Journal of …, 2017 - cell.com
One major challenge encountered with interpreting human genetic variants is the limited
understanding of the functional impact of genetic alterations on biological processes. …