User profiles for L. Mahimainathan

lenin mahimainathan

Verified email at ttuhsc.edu
Cited by 3436

[HTML][HTML] Requirement of BMP-2-induced phosphatidylinositol 3-kinase and Akt serine/threonine kinase in osteoblast differentiation and Smad-dependent BMP-2 gene …

…, R Nishimura, A Celeste, L Mahimainathan… - Journal of Biological …, 2002 - ASBMB
The mechanism by which bone morphogenetic protein-2 (BMP-2) induces osteoblast
differentiation is not precisely known. We investigated the involvement of the phosphatidylinositol (…

A role for AMP-activated protein kinase in diabetes-induced renal hypertrophy

…, K Sataranatarajan, L Mahimainathan… - American Journal …, 2007 - journals.physiology.org
… Filters were washed three times by boiling for 1 min in 10% TCA containing 0.1 g/l … found
to be involved in high-glucose regulation of l-type pyruvate kinase gene expression in islet cells …

In-depth evaluation of a case of presumed myocarditis after the second dose of COVID-19 mRNA vaccine

…, M Narasimhan, QZ Li, L Mahimainathan… - Circulation, 2021 - Am Heart Assoc
A 52-year-old man presented to the emergency department≈ 90 min after the onset of
substernal chest pain. Three days before presentation, he received his second dose of mRNA-…

[HTML][HTML] Interleukin-18-induced human coronary artery smooth muscle cell migration is dependent on NF-κB-and AP-1-mediated matrix metalloproteinase-9 …

B Chandrasekar, S Mummidi, L Mahimainathan… - Journal of Biological …, 2006 - ASBMB
The proliferation and migration of arterial smooth muscle cells (SMCs) are key events in the
vascular restenosis that frequently follows angioplasty. Furthermore, SMC migration and …

Clinical evaluation of the Abbott Alinity SARS-CoV-2 spike-specific quantitative IgG and IgM assays among infected, recovered, and vaccinated groups

M Narasimhan, L Mahimainathan, E Araj… - Journal of clinical …, 2021 - Am Soc Microbiol
The coronavirus disease 19 (COVID-19) pandemic continues to impose a significant burden
on global health infrastructure. While identification and containment of new cases remain …

[HTML][HTML] Identification of novel microRNAs in post-transcriptional control of Nrf2 expression and redox homeostasis in neuronal, SH-SY5Y cells

…, M Rathinam, G Henderson, L Mahimainathan - PloS one, 2012 - journals.plos.org
Nuclear factor-erythroid 2-related factor 2 (Nrf2/NFE2L2), a redox-sensitive transcription factor
plays a critical role in adaptation to cellular stress and affords cellular defense by initiating …

Mesangial cell hypertrophy by high glucose is mediated by downregulation of the tumor suppressor PTEN

L Mahimainathan, F Das, B Venkatesan… - Diabetes, 2006 - Am Diabetes Assoc
… in serum-free medium with 5 mmol/l glucose and incubated with medium containing 5 mmol/l
glucose plus 20 mmol/l mannitol as control and with 25 mmol/l glucose for 48 h. In the last …

SARS-CoV-2 antibody responses do not predict COVID-19 disease severity

…, JA SoRelle, QZ Li, L Mahimainathan… - American journal of …, 2020 - academic.oup.com
Objectives Initial reports indicate adequate performance of some serology-based severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) assays. However, additional studies …

[HTML][HTML] Serological response in lung transplant recipients after two doses of SARS-CoV-2 mRNA vaccines

M Narasimhan, L Mahimainathan, AE Clark, A Usmani… - Vaccines, 2021 - mdpi.com
Background: Lung-transplant (LT) recipients are at high risk for COVID-19 due to
immunosuppression and respiratory tropism of SARS-CoV-2. The information on the effect of …

Hydrogen peroxide responsive miR153 targets Nrf2/ARE cytoprotection in paraquat induced dopaminergic neurotoxicity

…, D Vedpathak, G Henderson, L Mahimainathan - Toxicology letters, 2014 - Elsevier
Epidemiological and animal studies suggest that environmental toxins including paraquat (PQ)
increase the risk of developing Parkinson's disease (PD) by damaging nigrostriatal …