Many studies have suggested a role for the members of the G 12 family of heterotrimeric G
proteins (Gα 12 and Gα 13 ) in oncogenesis and tumor cell growth. However, few studies …

Wnt proteins constitute a family of secreted signaling molecules that regulate highly conserved
pathways essential for development and, when aberrantly activated, drive oncogenesis in …

Background— Although, endothelial nitric oxide (NO) synthase (eNOS) is believed to
antagonize vascular remodeling induced by the angiotensin II (AngII) type-1 receptor, the exact …

Axin, a negative regulator of the Wnt signaling pathway, contains a canonical regulator of G
protein signaling (RGS) core domain. Herein, we demonstrate both in vitro and in cells that …

The heterotrimeric G protein G 12 has been implicated in such cellular regulatory processes
as cytoskeletal rearrangement, cell-cell adhesion, and oncogenic transformation. Although …

Protease-activated receptors (PARs), such as PAR1 and PAR2, have been implicated in the
regulation of endothelial NO production. We hypothesized that PAR1 and PAR2 distinctly …

Signal transduction through heterotrimeric G proteins results in a wide variety of cellular
responses initiated by an interaction between G proteins and G protein-coupled receptors. …

There has been limited attention to cancer narrative public service announcements (CNPSAs)
despite their potential to educate and engage consumers. Attributes of “well-told” stories …

In the mid-thirteenth century, the Cistercian chronicler Gilles of Orval recorded an episode of
charitable endeavour on behalf of people with leprosy that renders a dramatic scene of …

Introduction. Avoiding intubation and promoting noninvasive modes of ventilator support
including continuous positive airway pressure (CPAP) in preterm infants minimizes lung injury …