Allosteric modulation of the cannabinoid CB1 receptor

…, M Easson, R Goodwin, A McLean, L McIntosh… - Molecular …, 2005 - ASPET
We investigated the pharmacology of three novel compounds, Org 27569 (5-chloro-3-ethyl-1H-indole-2-carboxylic
acid [2-(4-piperidin-1-yl-phenyl)-ethyl]-amide), Org 27759 (3-ethyl-5-…

Role of copper ions and cytochrome P450 in the vasodilator actions of the nitroxyl anion generator, Angeli's salt, on rat aorta

S Nelli, L McIntosh, W Martin - European journal of pharmacology, 2001 - Elsevier
Since copper ions catalyse the oxidation of nitroxyl anion to nitric oxide, we investigated
whether this might explain the vasodilator actions of the nitroxyl generator, Angeli's salt, in rat …

Discovery and optimisation of a selective non-steroidal glucocorticoid receptor antagonist

…, SJ Lusher, S MacDonald, L McIntosh… - Bioorganic & medicinal …, 2011 - Elsevier
High-throughput screening of 3.87million compounds delivered a novel series of non-steroidal
GR antagonists. Subsequent rounds of optimisation allowed progression from a non-…

A child dies

J Lishman, L McIntosh, B McIntosh - Practice, 1989 - Taylor & Francis
… In this paper Lorraine and Brian, as parents, and I, as their social worker, try to show how
these processes of grief were experienced at an individual and personal level, and what …

The Sedimentology and Stratigraphy of the Lower Cretaceous (Albian) Viking Formation, Joffre/Mikwan Fields, Alberta, Canada

L McIntosh - 1995 - macsphere.mcmaster.ca
The Joffre/Mikwan field {Lower Cretaceous, Viking Formation) is a long narrow sandbody
encased in marine mudstones. The sandbody trends northwest-southeast. Four cross-sections …

The returns to academic and vocational qualifications in Britain

L Dearden, S McIntosh, M Myck… - Bulletin of economic …, 2002 - Wiley Online Library
This paper uses data from the 1991 sweep of the National Child Development Study (NCDS)
and the 1998 Labour Force Survey (LFS) to provide a comprehensive analysis of the …

Neurokinin B receptor antagonism in women with polycystic ovary syndrome: a randomized, placebo-controlled trial

…, RA Anderson, S McIntosh… - The Journal of …, 2016 - academic.oup.com
Context: Polycystic ovary syndrome (PCOS), the most common endocrinopathy in women, is
characterized by high secretion levels of LH and T. Currently, there is no treatment licensed …

The returns to academic, vocational and basic skills in Britain

L Dearden, S McIntosh, M Myck… - DfEE Skills Task Force …, 2000 - voced.edu.au
This report contains a comprehensive analysis of the returns to a range of qualifications and
to basic literacy and numeracy skills in the UK. New information is provided on the returns to …

A discourse analysis of representational spaces: Writings of women independent traveller

…, L Friend, A McIntosh - Tourism: An International …, 2006 - hrcak.srce.hr
Since 1987 there has been a substantial growth in women travelling independently, with the
mature welltravelled woman seeking more than a holiday lying on the beach. In response to …

Clinical effectiveness and cost-effectiveness of a multifaceted podiatry intervention for falls prevention in older people: a multicentre cohort randomised controlled trial …

…, AM Keenan, SE Lamb, C McIntosh… - Health technology …, 2017 - eprints.whiterose.ac.uk
BACKGROUND: Falls are a serious cause of morbidity and cost to individuals and society.
Evidence suggests that foot problems and inappropriate footwear may increase the risk of …