Monoamine transporters (MATs) carry out neurotransmitter reuptake from the synaptic cleft,
a key step in neurotransmission, which is targeted in the treatment of neurological disorders. …

The human monoamine transporters (MATs) facilitate the reuptake of the neurotransmitters
serotonin, dopamine, and norepinephrine from the synaptic cleft. Imbalance in …

The human serotonin transporter (hSERT) terminates serotonergic signaling through reuptake
of neurotransmitter into presynaptic neurons and is a target for many antidepressant drugs…

Selective inhibitors of the human serotonin transporter (hSERT) have been first-line treatment
against depression for several decades. Recently, vortioxetine was approved as a new …

5-Hydroxytryptamine 3 (5-HT 3 ) receptors are ligand-gated ion channels that mediate
neurotransmission by serotonin in the central nervous system. Pharmacological inhibition of 5-HT …

The transporters for the neurotransmitters serotonin and dopamine (SERT and DAT, respectively)
are targets for drugs used in the treatment of mental disorders and widely used drugs …

The serotonin transporter (SERT) belongs to the monoamine transporter family, which also
includes the dopamine and norepinephrine transporters. SERT is essential for regulating …

The binding-induced fluorescence of 4-(4-(dimethylamino)-phenyl)-1-methylpyridinium (APP
+ ) and two new serotonin transporter (SERT)-binding fluorescent analogues, 1-butyl-4-[4-(1…

Amyloid fibrils are protein aggregates formed by protein assembly through cross β structures.
Inhibition of amyloid fibril formation may contribute to therapy against amyloid-related …

The 5-hydroxytryptamine (5-HT) type 3 receptor is a member of the cysteine (Cys)-loop
receptor super family of ligand-gated ion channels in the nervous system and is a clinical target …