Recent studies have revealed a positive correlation between astrocyte apoptosis and rapid
disease progression in persons with neurodegenerative diseases. Glycogen synthase …

HIV type 1 (HIV-1)-associated dementia (HAD) is believed to occur due to aberrant activation
of monocyte-derived macrophages and brain-resident microglial cells by viral proteins as …

The pathogenesis of human immunodeficiency virus type 1 (HIV‐1)‐associated dementia is
mediated by neuronal dysfunction and death, brought about by the action of soluble …

Human immunodeficiency virus dementia (HIV-D) is a nonfocal central nervous system
manifestation characterized by cognitive, behavioral, and motor abnormalities. The …

Activity of the transcription factor nuclear factor‐κB (NF‐κB) has been shown to be necessary
for maintaining neuronal viability. In cultured rat cerebellar granule neurons, trophic factor …

Nonclassical MHC class Ib (class Ib) genes are found in all jawed vertebrates, and their
products are hypothesized to be indicators of intracellular stress and malignancy. They may be …

OBJECTIVE: Neurotrophin receptor signaling has been increasingly recognized as an
important factor in the development and progression of a variety of malignancies. In order to …

Activation of nuclear factor-κB (NF-κB), a key feature of the neurotrophin signaling, has been
shown to be critical for neuronal survival under pathologic settings. However, the precise …

Background Human immunodeficiency virus type 1 (HIV-1) infection frequently causes
neurologic disease, which is the result of viral replication and activation of macrophages and …

The role of transposable elements in sculpting the genome is well appreciated but remains
poorly understood. Some organisms, such as humans, do not have active transposons; …