Rationale: The forced swimming test (FST) is a behavioral test in rodents that predicts the
clinical efficacy of many types of antidepressant treatments. Recently, a behavior sampling …

The present study examined the regional localization of corticotropin-releasing factor (CRF)-
and 5-hydroxytryptamine (5-HT)-immunoreactive (IR) fibers within the rat dorsal raphe …

The serotonergic dorsal raphe nucleus is innervated by corticotropin-releasing factor (CRF)
and expresses CRF receptors, suggesting that endogenous CRF impacts on this system. …

The effects of forced swimming for 30 min on extracellular 5-hydroxytryptamine (5-HT) levels
were examined in five brain regions in rats using in vivo microdialysis. A single dialysis …

The dorsal (DR) and median raphe (MR) nuclei contain 5-hydroxytryptamine (serotonin, 5-HT)
cell bodies that give rise to the majority of the ascending 5-HT projections to the forebrain …

We used in vivo microdialysis to examine extracellular levels of 5-hydroxytryptamine (5-HT)
and 5-hydroxyindoleacetic acid (5-HIAA) in the striatum and the lateral septum during the …

The effects of application of five different stressors on extracellular 5-hydroxytryptamine and
5-hydroxyindoleacetic acid in the striatum and hippocampus were compared using in vivo …

Previous studies have identified potential antidepressant effects of buprenorphine (BPN), a
drug with high affinity for mu opioid receptor (MORs) and kappa opioid receptors (KORs) and …

Stress-related psychiatric disorders such as anxiety and depression involve dysfunction of the
serotonin [5-hydroxytryptamine (5-HT)] system. Previous studies have found that the stress …

Emerging evidence indicates the involvement of GPR55 and its proposed endogenous ligand,
lysophosphatidylinositol (LPI), in nociception, yet their role in central pain processing has …