Identification of survival genes in human glioblastoma cells by small interfering RNA screening
…, F Zhang, PR McDonald, TY Shun, MD Lewen… - Molecular …, 2009 - ASPET
Target identification and validation remain difficult steps in the drug discovery process, and
uncovering the core genes and pathways that are fundamental for cancer cell survival may …
uncovering the core genes and pathways that are fundamental for cancer cell survival may …
Uveitis reactivation in children treated with tumor necrosis factor alpha inhibitors
…, MD Lewen, JH Kempen, MD Mills - American journal of …, 2015 - Elsevier
… Lerman, MD, PhD, MSCE is an Instructor in Pediatric Rheumatology at The Children's Hospital
of Philadelphia. She completed her PhD in immunology at the University of Pennsylvania, …
of Philadelphia. She completed her PhD in immunology at the University of Pennsylvania, …
[HTML][HTML] Cerebral microdialysis for protein biomarker monitoring in the neurointensive care setting–a technical approach
… showed that the proteins adsorbed onto the MD membrane may be lost to biomarker analysis
in the dialysate since they are prevented from crossing the MD membrane (13). In addition, …
in the dialysate since they are prevented from crossing the MD membrane (13). In addition, …
Interstitial F2-Isoprostane 8-Iso-PGF2α As a Biomarker of Oxidative Stress after Severe Human Traumatic Brain Injury
F Clausen, N Marklund, A Lewén, P Enblad… - Journal of …, 2012 - liebertpub.com
… -glycerol has also been implicated as a biomarker of oxidative stress (Clausen et al.,
2005; Lewen and Hillered, 1998). The strong correlation between MD-8-iso-PGF 2α and MD-…
2005; Lewen and Hillered, 1998). The strong correlation between MD-8-iso-PGF 2α and MD-…
Arterial Oxygenation in Traumatic Brain Injury—Relation to Cerebral Energy Metabolism, Autoregulation, and Clinical Outcome
…, L Hillered, P Enblad, A Lewén - Journal of intensive …, 2021 - journals.sagepub.com
… -lactate-/pyruvate ratio (LPR) above 25 had significantly lower arterial oxygen levels than
those with limited MD-pyruvate supply and normal MD-LPR (P = .001) this day. Arterial …
those with limited MD-pyruvate supply and normal MD-LPR (P = .001) this day. Arterial …
Cerebral microdialysis monitoring of energy metabolism: relation to cerebral blood flow and oxygen delivery in aneurysmal subarachnoid hemorrhage
…, E Rostami, E Ronne-Engström, A Lewén… - Journal of …, 2023 - journals.lww.com
… A compensated/normal MD pattern (MD-LPR <25) was … with a MD pattern of poor substrate
supply (MD-LPR >25, MD-… MD catheter was associated with lower MD-glucose, higher …
supply (MD-LPR >25, MD-… MD catheter was associated with lower MD-glucose, higher …
[PDF][PDF] Identification of Survival Genes in Human Glioblastoma Cells Using siRNA Screening
…, PR McDonald, TY Shun, MD Lewen… - Molecular …, 2009 - academia.edu
228 Introduction: 447 Discussion: 1,624 Abbreviations: siRNA, short interfering RNA; PSMB4,
proteasome subunit beta 4; NF-κB, nuclear factor kappa-light-chain-enhancer of activated …
proteasome subunit beta 4; NF-κB, nuclear factor kappa-light-chain-enhancer of activated …
Evaluation of left ventricular systolic and diastolic dysfunction during transient myocardial ischemia produced by angioplasty
AJ Labovitz, MK Lewen, M Kern, M Vandormael… - Journal of the American …, 1987 - Elsevier
Acute myocardial ischemia is known to cause impairment of both left ventricular systolic and
diastolic function. To further investigate these changes as well as their relation to common …
diastolic function. To further investigate these changes as well as their relation to common …
Incidence of non-syndromic and syndromic craniosynostosis in Sweden
…, G Maltese, MB Söfteland, A Lewén… - Journal of …, 2022 - journals.lww.com
Premature craniosynostosis is a rare condition, with a wide range of incidence estimations
in the literature. The aim of this study was to establish the current incidence among the …
in the literature. The aim of this study was to establish the current incidence among the …
[HTML][HTML] Intracranial pressure-and cerebral perfusion pressure threshold-insults in relation to cerebral energy metabolism in aneurysmal subarachnoid hemorrhage
…, A Hånell, T Howells, E Ronne-Engström, A Lewén… - Acta …, 2022 - Springer
… 25 mmHg thresholds correlated with lower MD-glucose and increased MD-lactate-pyruvate
ratio … ) also correlated with a MD pattern of poor cerebral substrate supply (MD-LPR > 40 and …
ratio … ) also correlated with a MD pattern of poor cerebral substrate supply (MD-LPR > 40 and …