The cardiovascular actions of cannbinoids are complex. In general they cause vasorelaxation
in isolated blood vessels, while in anaesthetised animals they cause multiphasic …

The prototypic endocannabinoid, anandamide, and synthetic analogues have been shown
to elicit pressor and depressor effects, bradycardia, vasorelaxation, and inhibition of …

Background and purpose: The endocannabinoid N‐arachidonoylethanolamide (anandamide)
is co‐synthesized with other N‐acylethanolamides, namely N‐palmitoylethanolamide (…

We have shown that the major active agent of Cannabis sativa, Δ 9 -tetrahydrocannabinol,
activates peroxisome proliferator-activated receptor gamma [PPARγ, O'Sullivan, SE, Tarling, …

Endocannabinoids are blood borne and may also be secreted by the endothelium. Accordingly,
there has been interest in the interactions between (endo)cannabinoids and blood cells. …

Cannabinoids have widespread effects on the cardiovascular system, only some of which
are mediated via G-protein-coupled cell surface receptors. The active ingredient of cannabis, …

We have investigated the involvement of nitric oxide and K + channels in the vasorelaxant
responses to physiologically‐relevant concentrations of testosterone in the rat isolated …

Since the identification of nitric oxide (NO) as an important mediator of endothelium-dependent
relaxation, it has become clear that there is an additional endothelial relaxant factor, …

Pre-eclampsia is a pregnancy-specific disorder associated with hypertension and proteinuria,
characterized by alterations in endothelial cell function. In the present study we have …

We have used the isolated, buffer‐perfused, superior mesenteric arterial bed of male and
female rats to assess the relative contributions of nitric oxide (NO) and the endothelium‐…