Important functions of the vascular endothelium, including permeability, production of
antithrombotic factors, and control of vascular tone, are regulated by changes in intracellular Ca 2+ …

Reactive oxygen species (ROS) can have divergent effects in cerebral and peripheral
circulations. We found that Ca 2+ -permeable transient receptor potential ankyrin 1 (TRPA1) …

Maintaining constant blood flow in the face of fluctuations in blood pressure is a critical
autoregulatory feature of cerebral arteries. An increase in pressure within the artery lumen …

We previously reported that binding of prorenin to the (pro)renin receptor (PRR) plays a major
role in brain angiotensin II formation and the development of deoxycorticosterone acetate (…

The (pro)renin receptor (PRR), which binds both renin and prorenin, is a newly discovered
component of the renin–angiotensin system that is highly expressed in the central nervous …

… * PW Pires and MN Sullivan contributed equally to this work. … * PW Pires and MN
Sullivan contributed equally to this work. … to PW Pires and 15PRE22670024 to MN Sullivan. …

… Sullivan, Michael Francis, Natalie L. Pitts, Mark S. Taylor and Scott Earley … Performed data
analysis: Sullivan and Earley. Wrote or contributed to the writing of the manuscript: Sullivan …

Proliferation of airway smooth muscle cells (ASMCs) contributes to the remodeling and
irreversible obstruction of airways during severe asthma, but the mechanisms underlying this …

Recent studies have shown that pyruvic acid can produce higher-molecular-weight
compounds upon irradiation in the aqueous phase. These compounds can contribute to the …

Holes within the internal elastic lamina (IEL) of blood vessels are sites of fenestration
allowing for passage of diffusible vasoactive substances and interface of endothelial cell …