Endothelial dysfunction in diabetes: from mechanisms to therapeutic targets
…, S Gagliardi, C Nacci, MR Carratu… - Current medicinal …, 2009 - ingentaconnect.com
Micro- and macrovascular complications are major causes of disability and death in patients
with diabetes mellitus. Functional impairment of endothelial activity precedes the …
with diabetes mellitus. Functional impairment of endothelial activity precedes the …
Therapeutic targeting of the mTOR‐signalling pathway in cancer: benefits and limitations
…, C Marasco, A Vacca, MR Carratù - British journal of …, 2014 - Wiley Online Library
The mammalian target of rapamycin ( mTOR ) plays an important role in the regulation of
protein translation, cell growth and metabolism. The mTOR protein forms two distinct multi‐…
protein translation, cell growth and metabolism. The mTOR protein forms two distinct multi‐…
[HTML][HTML] Cannabidiol reduces Aβ-induced neuroinflammation and promotes hippocampal neurogenesis through PPARγ involvement
…, V Latina, D De Filippis, M Cipriano, MR Carratù… - PloS one, 2011 - journals.plos.org
Peroxisome proliferator-activated receptor-γ (PPARγ) has been reported to be involved in
the etiology of pathological features of Alzheimer's disease (AD). Cannabidiol (CBD), a …
the etiology of pathological features of Alzheimer's disease (AD). Cannabidiol (CBD), a …
Synergistic effects of fumonisin B1 and ochratoxin A: are in vitro cytotoxicity data predictive of in vivo acute toxicity?
…, I Baudrimont, P Borracci, S Moukha, MR Carratù - Toxicology, 2004 - Elsevier
Contamination of food and feeds by mycotoxins is a major problem of human and animals
health concern which is also extremely detrimental to economy. Mycotoxins producing moulds …
health concern which is also extremely detrimental to economy. Mycotoxins producing moulds …
Effects of perinatal exposure to delta-9-tetrahydrocannabinol on the emotional reactivity of the offspring: a longitudinal behavioral study in Wistar rats
…, T Cassano, T Macheda, P Dipasquale, MR Carratù… - …, 2008 - Springer
Rationale The endocannabinoid system plays a crucial role in the control of emotionality
and recent clinical findings have shown that heavy prenatal exposure to cannabis is …
and recent clinical findings have shown that heavy prenatal exposure to cannabis is …
[HTML][HTML] Emerging roles for ion channels in ovarian cancer: Pathomechanisms and pharmacological treatment
C Altamura, MR Greco, MR Carratù, RA Cardone… - Cancers, 2021 - mdpi.com
Simple Summary Around 4% of cancer deaths in the world was associated to ovarian cancer
(OC), making it the eighth most common cause of death in women. Increasing evidence …
(OC), making it the eighth most common cause of death in women. Increasing evidence …
[HTML][HTML] Palmitoylethanolamide exerts neuroprotective effects in mixed neuroglial cultures and organotypic hippocampal slices via peroxisome proliferator-activated …
…, M Valenza, C Stecca, G Esposito, MR Carratù… - Journal of …, 2012 - Springer
Background In addition to cytotoxic mechanisms directly impacting neurons, β-amyloid (Aβ)-induced
glial activation also promotes release of proinflammatory molecules that may self-…
glial activation also promotes release of proinflammatory molecules that may self-…
Epigenetic properties of fumonisin B1: cell cycle arrest and DNA base modification in C6 glioma cells
TA Mobio, R Anane, I Baudrimont, MR Carratú… - Toxicology and applied …, 2000 - Elsevier
Fumonisin B 1 produced by the fungus Fusarium moniliforme is a member of a new class of
sphinganine analogue mycotoxins that occur widely in the food chain. Epidemiological …
sphinganine analogue mycotoxins that occur widely in the food chain. Epidemiological …
Endothelial dysfunction in mice with streptozotocin-induced type 1 diabetes is opposed by compensatory overexpression of cyclooxygenase-2 in the vasculature
…, A Mauro, A Zigrino, MR Carratu… - …, 2009 - academic.oup.com
Cardiovascular complications of diabetes result from endothelial dysfunction secondary to
persistent hyperglycemia. We investigated potential compensatory mechanisms in the …
persistent hyperglycemia. We investigated potential compensatory mechanisms in the …
[HTML][HTML] A silybin-phospholipids complex counteracts rat fatty liver degeneration and mitochondrial oxidative changes
…, A Liquori, D Ferri, MR Carratù… - World Journal of …, 2013 - ncbi.nlm.nih.gov
AIM: To investigate the effectiveness of antioxidant compounds in modulating mitochondrial
oxidative alterations and lipids accumulation in fatty hepatocytes. METHODS: Silybin-…
oxidative alterations and lipids accumulation in fatty hepatocytes. METHODS: Silybin-…