This meta-analysis of 163 randomized trials (including 59 dissertations) examines a number
of questions not studied in previous syntheses. These include differences in outcome …

Motor proteins are nature's solution for directing movement at the molecular level. The field
of artificial molecular motors takes inspiration from these tiny but powerful machines. …

Figure 1 Predicted structure of clusterin. The cartoon shows mature human clusterin after
cleavage of its 22-mer signal peptide and internal cleavage at its Arg227–Ser228 bond, …

Background Primary open-angle glaucoma (POAG) is one of the leading causes of blindness
in the United States and worldwide. Three to 6 million people in the United States are at …

Background The Ocular Hypertension Treatment Study (OHTS) has shown that topical ocular
hypotensive medication is effective in delaying or preventing the onset of primary open-…

Multiple sclerosis (MS) is a heterogenous autoimmune disease in which autoreactive
lymphocytes attack the myelin sheath of the central nervous system. B lymphocytes in the …

Studies into the effects of ultrafine particles in the lung have shown adverse effects considered
to be due in part to the particle size. Air pollution particles (PM 10 ) are associated with …

Urine has long been a “favored” biofluid among metabolomics researchers. It is sterile, easy-to-obtain
in large volumes, largely free from interfering proteins or lipids and chemically …

Objective. To determine the range of antinuclear antibodies (ANA) in “healthy” individuals
compared with that in patients with systemic lupus erythematosus (SLE), systemic sclerosis (…

Background. Encephalitis continues to result in substantial morbidity and mortality
worldwide. Advances in diagnosis and management have been limited, in part, by a lack of …