We have developed a host cell reactivation assay of DNA repair utilizing UV-treated plasmid
vectors. The assay primarily reflects cellular repair of transcriptional activity of damaged …

We used a simian virus 40-based shuttle vector plasmid, pZ189, to determine the role of
pyrimidine cyclobutane dimers in UV light-induced mutagenesis in monkey cells. The vector …

Postmitochondrial supernatant from rat liver and kidney homogenates transformed cysteine
into a mutagen that reverted bacteria of the strain Salmonella typhimurium TA100 to histidine …

A shuttle vector plasmid, pZ189, was utilized to assess the types of mutations that cells from
a patient with xeroderma pigmentosum, complementation group D, introduce into ultraviolet (…

… acetyltransferase, CAT) was 12-fold more sensitive to ultraviolet inactivation in xeroderma
pigmentosum complementation group A than in repair proficient cells (ProtiC-SabljiC and …

The metabolism of carcinogens in fish was examined by measuring the activation of
different polycyclic aromatic hydrocarbons (PAH) by carp (Cyprinus carpio L.) liver post-…

We wished to determine whether simian virus 40 (SV40)-transformed xeroderma pigmentosum
cells, despite their defective DNA repair, were suitable for DNA-mediated gene transfer …

Results of various studies have shown that male Swiss Webster mice are more susceptible
to toxic effects of vinylidene chloride (VDC.) than are females of the same mouse strain, …

Fibroblasts from a patient with xeroderma pigmentosum complementition group D were
treated with Simian virus 40 to establish a transformed cell line suitable for studies of DNA-…

Xeroderma pigmentosum patients, in addition to ultraviolet-induced skin cancers, have an
increased prevalence of neoplasms occuring in sites shielded from ultraviolet radiation. We …