Mannose‐functionalized mesoporous silica nanoparticles for efficient two‐photon photodynamic therapy of solid tumors

M GaryBobo, Y Mir, C Rouxel, D Brevet… - Angewandte …, 2011 - Wiley Online Library
In the context of national systematic screenings for cancer, photodynamic therapy (PDT) has
arisen as an alternative to chemo-and radiotherapy for the non-invasive selective …

Rimonabant reduces obesity-associated hepatic steatosis and features of metabolic syndrome in obese Zucker fa/fa rats

M Gary-Bobo, G Elachouri, JF Gallas, P Janiak… - Hepatology, 2007 - journals.lww.com
This study investigated the effects of rimonabant (SR141716), an antagonist of the cannabinoid
receptor type 1 (CB1), on obesity-associated hepatic steatosis and related features of …

Mannose 6-phosphate receptor targeting and its applications in human diseases

M Gary-Bobo, P Nirdé, A Jeanjean… - Current medicinal …, 2007 - ingentaconnect.com
The cation-independent mannose 6-phosphate receptor is a multifunctional protein which
binds at the cell surface to two distinct classes of ligands, the mannose 6-phosphate (M6P) …

[PDF][PDF] Two-photon excitation of porphyrin-functionalized porous silicon nanoparticles for photodynamic therapy

…, A Gallud, A Chaix, E Bouffard, M Gary-Bobo… - Adv. Mater, 2014 - academia.edu
Nanomaterials offer the potential for minimally invasive and focal therapies to reduce side-effects
associated with systemic administration of anticancer drugs. Clinical treatment …

Mannose-targeted mesoporous silica nanoparticles for photodynamic therapy

D Brevet, M Gary-Bobo, L Raehm, S Richeter… - Chemical …, 2009 - pubs.rsc.org
… David Brevet‡ a , Magali Gary-Bobo‡ b , Laurence Raehm a , Sébastien Richeter a ,
Ouahiba Hocine a , Kassem Amro a , Bernard Loock c , Pierre Couleaud d , Céline Frochot§ …

Cancer therapy improvement with mesoporous silica nanoparticles combining targeting, drug delivery and PDT

M Gary-Bobo, O Hocine, D Brevet, M Maynadier… - International journal of …, 2012 - Elsevier
The synthesis of Mesoporous Silica Nanoparticles (MSN) covalently encapsulating fluoresceine
or a photosensitizer, functionalized with galactose on the surface is described. Confocal …

The cannabinoid CB1 receptor antagonist rimonabant (SR141716) inhibits cell proliferation and increases markers of adipocyte maturation in cultured mouse 3T3 …

M Gary-Bobo, G Elachouri, B Scatton, G Le Fur… - Molecular …, 2006 - ASPET
Adipocyte cell proliferation is an important process in body fat mass development in obesity.
Adiponectin or Acrp30 is an adipocytokine exclusively expressed and secreted by adipose …

Two‐Photon‐Triggered Drug Delivery via Fluorescent Nanovalves

…, M Maynadier, A Gallud, M GaryBobo… - Small, 2014 - Wiley Online Library
… , Magali Gary-Bobo,* Marcel Garcia, Jie Lu, Fuyuhiko Tamanoi, Daniel P. Ferris, Derrick
Tarn, and Jeffrey I. Zink* the systems described so far require UV-Vis light which limits their …

Two‐Photon‐Triggered Drug Delivery in Cancer Cells Using Nanoimpellers

…, M Blanchard‐Desce, M GaryBobo… - Angewandte …, 2013 - Wiley Online Library
Nowadays, remote activation of nanoparticles (NPs) by light for biomedical applications has
become an important area of research.[1] Among the different nano-objects, mesoporous …

Pyclen-Based Ln(III) Complexes as Highly Luminescent Bioprobes for In Vitro and In Vivo One- and Two-Photon Bioimaging Applications

…, A Grichine, S Brasselet, M Gary-Bobo… - Journal of the …, 2020 - ACS Publications
In addition to the already described ligand L 4a , two pyclen-based lanthanide chelators, L
4b and L 4c , bearing two specific picolinate two-photon antennas (tailor-made for each …