Role in the selectivity of neonicotinoids of insect-specific basic residues in loop D of the nicotinic acetylcholine receptor agonist binding site

M Shimomura, M Yokota, M Ihara, M Akamatsu… - Molecular …, 2006 - ASPET
The insecticide imidacloprid and structurally related neonicotinoids act selectively on insect
nicotinic acetylcholine receptors (nAChRs). To investigate the mechanism of neonicotinoid …

Splice-variant-and stage-specific RNA editing of the Drosophila GABA receptor modulates agonist potency

…, SD Buckingham, M Papadaki, M Yokota… - Journal of …, 2009 - Soc Neuroscience
The molecular diversity of many gene products functioning in the nervous system is enhanced
by alternative splicing and adenosine-to-inosine editing of pre-mRNA. Using RDL, a …

Roles of loop C and the loop B–C interval of the nicotinic receptor α subunit in its selective interactions with imidacloprid in insects

M Shimomura, M Yokota, K Matsuda, DB Sattelle… - Neuroscience …, 2004 - Elsevier
To elucidate the mechanism of selective action of imidacloprid on insect nicotinic acetylcholine
receptors (nAChRs), we examined the roles of loop C and the loop B–C interval region in …

Insect-vertebrate chimeric nicotinic acetylcholine receptors identify a region, loop B to the N-terminus of the Drosophila Dα2 subunit, which contributes to neonicotinoid …

M Shimomura, H Satoh, M Yokota, M Ihara… - Neuroscience …, 2005 - Elsevier
A chimera based on the chicken α4 nicotinic acetylcholine receptor (nAChR) subunit
containing an insert from loop B to the N-terminus of the Drosophila melanogaster Dα2 (=SAD) …

Combinatorial mutations in loops D and F strongly influence responses of the α7 nicotinic acetylcholine receptor to imidacloprid

M Shimomura, M Yokota, M Okumura, K Matsuda… - Brain research, 2003 - Elsevier
The nitro group of a neonicotinoid, imidacloprid, plays a key role in its selective actions on
insect nicotinic acetylcholine receptors (nicotinic AChRs) and is postulated to bind close to …

α7 mutants mimicking atypical motifs (YxxCC of loop-C, and E to H at −1′ in TM2) in the C. elegans LEV-8 subunit affect nicotinic acetylcholine receptor function

PR Towers, L Pym, M Yokota, K Matsuda… - Invertebrate …, 2006 - Springer
The ACR-8-like group of C. elegans nicotinic acetylcholine receptor (nAChR) subunits contain
unusual motifs in the ACh binding site and in the −1′ position of transmembrane region …

PKA-dependent regulation of the histone lysine demethylase complex PHF2–ARID5B

A Baba, F Ohtake, Y Okuno, K Yokota, M Okada… - Nature cell …, 2011 - nature.com
Reversible histone methylation and demethylation are highly regulated processes that are
crucial for chromatin reorganization and regulation of gene transcription in response to …

[HTML][HTML] A simple and rapid detection system for oral bacteria in liquid phase for point-of-care diagnostics using magnetic nanoparticles

…, H Onodera, K Okita, S Yabukami, K Yokota… - AIP Advances, 2019 - pubs.aip.org
This study describes a user-friendly and rapid detection system of oral bacteria in the liquid
phase for point of care testing based on magnetic immunoassay. We focused on the …

[HTML][HTML] Visible-light-enhanced antibacterial activity of silver and copper co-doped titania formed on titanium via chemical and thermal treatments

K Suzuki, M Iwatsu, T Mokudai, M Furuya, K Yokota… - Molecules, 2023 - mdpi.com
Dental implants made of titanium (Ti) are used in dentistry, but peri-implantitis is a serious
associated problem. Antibacterial and osteoconductive Ti dental implants may decrease the …

Comparative study on sample preparation methods for the HPLC quantification of iturin from culture supernatant of an antagonistic Bacillus strain.

K Yokota, M Yatsuda, E Miwa, K Higuchi - 2012 - cabidigitallibrary.org
Iturin is one of the antimicrobial cyclic lipopeptides produced by antagonistic strains of
Bacillus spp. This study evaluated sample preparation methods for high-performance liquid …