Atrazine, one of the most commonly used herbicides worldwide, acts as an endocrine disruptor,
but the mechanism of its action has not been characterized. In this study, we show that …

Inexpensive genotyping methods are essential to modern genomics. Here we present QUILT,
which performs diploid genotype imputation using low-coverage whole-genome sequence …

Genetic variation segregates as linked sets of variants or haplotypes. Haplotypes and
linkage are central to genetics and underpin virtually all genetic and selection analysis. Yet, …

Repeated evolution can provide insight into the mechanisms that facilitate adaptation to novel
or changing environments. Here we study adaptation to altitude in two tropical butterflies, …

10.7554/eLife.42014.001 Evolutionary studies are often limited by missing data that are
critical to understanding the history of selection. Selection experiments, which reproduce rapid …

Complete genome sequencing has identified millions of DNA changes that differ between
humans and chimpanzees. Although a subset of these changes likely underlies important …

Pannexins are a newly discovered three-member family of proteins expressed in the brain
and peripheral tissues that belong to the superfamily of gap junction proteins. However, in …

Strongyloidiasis is a much-neglected but sometimes fatal soil born helminthiasis. The causing
agent, the small intestinal parasitic nematode Strongyloides stercoralis can reproduce …

Pituitary cells fire action potentials independently of external stimuli, and such spontaneous
electrical activity is modulated by a large variety of hypothalamic and intrapituitary agonists. …

The objective of the present study was to examine the susceptibility of diabetic rats with
cardiomyopathy to hypokalemia-induced ventricular fibrillation and to localize gap junction …