Epinephrine and norepinephrine act as potent agonists at the recombinant human dopamine D4 receptor

F Lanau, MT Zenner, O Civelli… - Journal of …, 1997 - Wiley Online Library
The catecholamines dopamine (DA), epinephrine (EP), and norepinephrine (NE) play important
roles in learning and memory, emotional states, and control of voluntary movement, as …

[HTML][HTML] Mutational analysis and molecular modeling of the allosteric binding site of a novel, selective, noncompetitive antagonist of the metabotropic glutamate 1 …

…, N Kratochwil, F Knoflach, MT Zenner… - Journal of Biological …, 2003 - ASBMB
A model of the rmGlu1 seven-transmembrane domain complexed with a negative allosteric
modulator, 1-ethyl-2-methyl-6-oxo-4-(1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)- 1,6-dihydro-…

Comparison of the binding pockets of two chemically unrelated allosteric antagonists of the mGlu5 receptor and identification of crucial residues involved in the …

…, N Kratochwil, A Mühlemann, MT Zenner… - Journal of …, 2006 - Wiley Online Library
Fenobam [N‐(3‐chlorophenyl)‐N′‐(4,5‐dihydro‐1‐methyl‐4‐oxo‐1H‐imidazole‐2‐yl)urea],
a clinically validated non‐benzodiazepine anxiolytic, has been shown to be a potent and …

Identification and characterization of a novel splice variant of the metabotropic glutamate receptor 5 gene in human hippocampus and cerebellum

…, F Knoflach, C Kratzeisen, MT Zenner… - Molecular brain …, 2002 - Elsevier
The G-protein coupled metabotropic glutamate receptor mGlu5 plays a pivotal role as a
modulator of synaptic plasticity, ion channel activity and excitotoxicity. Two splice variants, …

Me-talnetant and osanetant interact within overlapping but not identical binding pockets in the human tachykinin neurokinin 3 receptor transmembrane domains

…, C Bissantz, A Marcuz, C Kratzeisen, MT Zenner… - Molecular …, 2008 - ASPET
Recent clinical trials have indicated that neurokinin 3 receptor antagonists (S)-(+)-N-{{3-[1-benzoyl-3-(3,4-dichlorophenyl)-piperidin-3-yl]prop-1-yl}-4-phenylpiperidin-4-yl}-N-…

Expression and characterization of a dopamine D4R variant associated with delusional disorder

MT Zenner, M Nobile, R Henningsen, E Smeraldi… - FEBS …, 1998 - Wiley Online Library
Multiple genetic polymorphisms of the human dopamine D4 receptor (hD4R) have been
identified including a 12 bp repeat in exon 1 associated with a psychotic condition called …

Identification of a critical residue in the transmembrane domain 2 of tachykinin neurokinin 3 receptor affecting the dissociation kinetics and antagonism mode of …

…, C Kratzeisen, A Marcuz, MT Zenner… - Journal of medicinal …, 2009 - ACS Publications
In this study, we show that compound 3 (osanetant) binds with a pseudoirreversible,
apparent noncompetitive mode of antagonism at the guinea pig NK 3 , while it behaves …

[BOOK][B] Villard's Legacy: Studies in medieval technology, science and art in memory of Jean Gimpel

MT Zenner - 2017 - books.google.com
… Notre-Dame-la-Grande, Poitiers, detail, west façade, relief sculpture of two men
embracing (photo: Marie-Thérèse Zenner). … Marie-Thérèse Zenner, and is a past president. …

Villard de Honnecourt and Euclidean Geometry

MT Zenner - Nexus Network Journal, 2002 - Springer
Marie-Thérèse Zenner presents a brief overview of the survival of Latin Euclid within the
practical geometry tradition of builders, taking examples from an eleventh-century French …

A Proposal for Constructing the Plan and Elevation of a Romanesque Church Using Three Measures

MT Zenner - Ad Quadratum: The Practical Application of Geometry …, 2002 - taylorfrancis.com
… Data and analysis of coursing height survey in Zenner, Methods, pp. 122–47 and pp. 394–…
On this and other methodological considerations, see Marie-Thérèse Zenner, “AutoCAD as an …