BACKGROUND: Evidence indicates that infection with Ascaris lumbricoides may promote
development of allergy and asthma. OBJECTIVE: To study the role of tropomyosin, a pan-…

A novel antimicrobial peptide, anoplin, was purified from the venom of the solitary wasp
Anoplius samariensis. The sequence was mostly analyzed by mass spectrometry, which was …

Two novel inflammatory peptides were isolated from the venom of the social wasp Polybia
paulista. They had their molecular masses determined by ESI-MS and their primary …

Inflammatory peptides display different types of post-transcriptional modifications, such as C-terminal
amidation, that alter their biological activity. Here we describe the structural and …

This paper reports the purification and biochemical/pharmacological characterization of two
myotoxic phospholipases A 2 (PLA 2 s) from Bothrops brazili venom, a native snake from …

The peroxisome proliferator-activated receptor γ (PPARγ) is a target for treatment of type II
diabetes and other conditions. PPARγ full agonists, such as thiazolidinediones (TZDs), are …

Fire ants are well-known by their aggressive stinging behavior, causing many stinging incidents
of medical importance. The limited availability of fire ant venom for scientific and clinical …

Background Biopharmaceutical drugs are mainly recombinant proteins produced by
biotechnological tools. The patents of many biopharmaceuticals have expired, and biosimilars are …

Polycationic peptides may present their C-termini in either amidated or acidic form; however,
the effects of these conformations on the mechanisms of interaction with the membranes in …

Bees are recognized worldwide for their social, economic, and environmental value. In recent
decades they have been seriously threatened by diseases and high levels of pesticide use…