Rationale This review provides insight for the judicious selection of nicotine dose ranges and
routes of administration for in vivo studies. The literature is replete with reports in which a …

Epidemiological studies show that smoking is associated with a lower incidence of Parkinson's
disease (PD). This finding is important because it could provide clues about therapeutic …

… Relevant conflicts of interest/financial disclosures: Maryka Quik is on a patent for the use of …
Maryka Quik wrote the first draft and reviewed and critiqued the manuscript. Xiomara A. Perez …

Excess sugar consumption has been shown to contribute directly to weight gain, thus
contributing to the growing worldwide obesity epidemic. Interestingly, increased sugar …

The present studies were done to investigate the effect of long‐term nicotine treatment
against nigrostriatal damage in non‐human primates. Monkeys were administered nicotine in …

Tobacco use is a leading cause of preventable deaths worldwide. However, current smoking
cessation therapies have very limited long-term success rates. Considerable research effort …

Nicotinic acetylcholine receptors (nACh receptors2) in jawed vertebrates are prototypical
members of the multisubunit, neurotransmitter-gated superfamily of ion channels (ionotropic …

Involuntary movements, or dyskinesia, represent a debilitating complication of levodopa (L-dopa)
therapy for Parkinson's disease (PD). L-dopa-induced dyskinesia (LID) are ultimately …

Parkinson's disease is a debilitating movement disorder characterized by a generalized
dysfunction of the nervous system, with a particularly prominent decline in the nigrostriatal …

Nicotinic receptors are implicated in memory, learning, locomotor activity, and addiction.
Identification of the specific receptor subtypes that mediate these behaviors is essential for …