Expression and prognostic role of tumor suppressor gene PTEN/MMAC1/TEP1 in hepatocellular carcinoma

…, CS Changchien, CM Lee, MH Tai - … Journal of the …, 2003 - Wiley Online Library
BACKGROUND Inactivation of the tumor suppressor gene PTEN/MMAC1/TEP1, located on
chromosome 10q23, is a common event in advanced stages of diverse human malignancies. …

Human fatty acid synthase: properties and molecular cloning.

A Jayakumar, MH Tai, WY Huang… - Proceedings of the …, 1995 - National Acad Sciences
Fatty acid synthase (FAS; EC 2.3.1.85) was purified to near homogeneity from a human
hepatoma cell line, HepG2. The HepG2 FAS has a specific activity of 600 nmol of NADPH …

[HTML][HTML] Irisin mitigates oxidative stress, chondrocyte dysfunction and osteoarthritis development through regulating mitochondrial integrity and autophagy

…, HJ Ke, PC Kuo, CH Lee, JC Wu, WB Lu, MH Tai… - Antioxidants, 2020 - mdpi.com
Compromised autophagy and mitochondrial dysfunction downregulate chondrocytic activity,
accelerating the development of osteoarthritis (OA). Irisin, a cleaved form of fibronectin type …

Glucocorticoid receptor pathways are involved in the inhibition of astrocyte proliferation

KL Crossin, MH Tai, LA Krushel… - Proceedings of the …, 1997 - National Acad Sciences
In earlier studies, the neural cell adhesion molecule, N-CAM, was found to inhibit the proliferation
of rat astrocytes both in vitro and in vivo. To identify the gene targets involved, we used …

Expression of hepatoma‐derived growth factor in hepatocellular carcinoma: A novel prognostic factor

…, CM Lee, JH Chuang, MH Tai - … Journal of the …, 2003 - Wiley Online Library
BACKGROUND Hepatoma‐derived growth factor (HDGF) is a novel growth factor derived
from a hepatoma cell line. The current study was designed to elucidate the role of HDGF …

[HTML][HTML] Matrilysin (MMP-7) is a major matrix metalloproteinase upregulated in biliary atresia-associated liver fibrosis

…, CM Chen, CC Wang, YS Chen, CL Chen, MH Tai - Modern pathology, 2005 - Elsevier
Matrix metalloproteinases (MMPs) are the proteases responsible for tissue remodeling during
liver fibrosis caused by various disorders including biliary atresia. However, information …

The role of the PI3K/Akt/mTOR pathway in glial scar formation following spinal cord injury

…, CW Feng, HC Hung, SN Yang, NF Chen, MH Tai… - Experimental …, 2016 - Elsevier
Several studies suggest that glial scars pose as physical and chemical barriers that limit
neurite regeneration after spinal cord injury (SCI). Evidences suggest that the activation of the …

Differential recruitment of dentate gyrus interneuron types by commissural versus perforant pathways

TT Hsu, CT Lee, MH Tai, CC Lien - Cerebral cortex, 2016 - academic.oup.com
Gamma-aminobutyric acidergic (GABAergic) interneurons (INs) in the dentate gyrus (DG)
provide inhibitory control to granule cell (GC) activity and thus gate incoming signals to the …

Extracellular visfatin-promoted malignant behavior in breast cancer is mediated through c-Abl and STAT3 activation

…, CH Wang, SC Wu, YC Hsieh, SCS Hu, MH Tai… - Clinical Cancer …, 2016 - AACR
Purpose: Visfatin is an adipocytokine involved in cellular metabolism, inflammation, and
cancer. This study investigated the roles of extracellular visfatin in breast cancer, and explored …

Enhancement of regeneration with glia cell line–derived neurotrophic factor–transduced human amniotic fluid mesenchymal stem cells after sciatic nerve crush injury …

FC Cheng, MH Tai, ML Sheu, CJ Chen, DY Yang… - Journal of …, 2010 - thejns.org
Object Human amniotic fluid–derived mesenchymal stem cells (AFMSCs) have been shown
to promote peripheral nerve regeneration, and the local delivery of neurotrophic factors may …