User profiles for Mladen Paradzik
Mladen ParadžikRBI Verified email at irb.hr Cited by 251 |
[HTML][HTML] miRNA-guided reprogramming of glucose and glutamine metabolism and its impact on cell adhesion/migration during solid tumor progression
L Quirico, F Orso, S Cucinelli, M Paradzik… - Cellular and molecular …, 2022 - Springer
MicroRNAs (miRNAs) are small, non-coding RNAs about 22 nucleotides in length that regulate
the expression of target genes post-transcriptionally, and are highly involved in cancer …
the expression of target genes post-transcriptionally, and are highly involved in cancer …
[HTML][HTML] Integrin crosstalk contributes to the complexity of signalling and unpredictable cancer cell fates
Integrins are heterodimeric cell surface receptors composed of α and β subunits that control
adhesion, proliferation and gene expression. The integrin heterodimer binding to ligand …
adhesion, proliferation and gene expression. The integrin heterodimer binding to ligand …
[HTML][HTML] KANK2 links αVβ5 focal adhesions to microtubules and regulates sensitivity to microtubule poisons and cell migration
Integrins are heterodimeric glycoproteins that bind cells to extracellular matrix. Upon integrin
clustering, multimolecular integrin adhesion complexes (IACs) are formed, creating links to …
clustering, multimolecular integrin adhesion complexes (IACs) are formed, creating links to …
Apigenin, a dietary flavonoid, induces apoptosis, DNA damage, and oxidative stress in human breast cancer MCF-7 and MDA MB-231 cells
Apigenin is found in several dietary plant foods such as vegetables and fruits. To investigate
potential anticancer properties of apigenin on human breast cancer, ER-positive MCF-7 and …
potential anticancer properties of apigenin on human breast cancer, ER-positive MCF-7 and …
[HTML][HTML] Stroma-derived miR-214 coordinates tumor dissemination
…, F Virga, D Dettori, A Dalmasso, M Paradzik… - Journal of Experimental …, 2023 - Springer
Background Tumor progression is based on a close interaction between cancer cells and
Tumor MicroEnvironment (TME). Here, we focus on the role that Cancer Associated …
Tumor MicroEnvironment (TME). Here, we focus on the role that Cancer Associated …
Differential effects of integrin αv knockdown and cilengitide on sensitization of triple-negative breast cancer and melanoma cells to microtubule poisons
Low survival rates of patients with metastatic triple-negative breast cancer (TNBC) and
melanoma, in which current therapies are ineffective, emphasize the need for new therapeutic …
melanoma, in which current therapies are ineffective, emphasize the need for new therapeutic …
[HTML][HTML] Ancient origins of cytoskeletal crosstalk: Spectraplakin-like proteins precede the emergence of cortical microtubule stabilization complexes as crosslinkers
T Paradžik, II Podgorski, T Vojvoda Zeljko… - International journal of …, 2022 - mdpi.com
Adhesion between cells and the extracellular matrix (ECM) is one of the prerequisites for
multicellularity, motility, and tissue specialization. Focal adhesions (FAs) are defined as protein …
multicellularity, motility, and tissue specialization. Focal adhesions (FAs) are defined as protein …
[HTML][HTML] Sirt3 exerts its tumor-suppressive role by increasing p53 and attenuating response to estrogen in MCF-7 cells
Estrogen (E2) is a major risk factor for the initiation and progression of malignancy in estrogen
receptor (ER) positive breast cancers, whereas sirtuin 3 (Sirt3), a major mitochondrial …
receptor (ER) positive breast cancers, whereas sirtuin 3 (Sirt3), a major mitochondrial …
Gene expression in formalin-fixed paraffin-embedded lymph nodes
Elucidation of molecular pathways involved in development of human lymphoma requires
efficient methods for tackling gene expression in lymph nodes. Expression studies of …
efficient methods for tackling gene expression in lymph nodes. Expression studies of …
[HTML][HTML] The Tongue Squamous Carcinoma Cell Line Cal27 Primarily Employs Integrin α6β4-Containing Type II Hemidesmosomes for Adhesion Which Contribute to …
…, J Zha, K Čuljak, M Tomić, M Paradžik… - Frontiers in cell and …, 2021 - frontiersin.org
Integrins are heterodimeric cell surface glycoproteins used by cells to bind to the extracellular
matrix (ECM) and regulate tumor cell proliferation, migration and survival. A causative …
matrix (ECM) and regulate tumor cell proliferation, migration and survival. A causative …