User profiles for Mladen Paradzik

Mladen Paradžik

RBI
Verified email at irb.hr
Cited by 251

[HTML][HTML] miRNA-guided reprogramming of glucose and glutamine metabolism and its impact on cell adhesion/migration during solid tumor progression

L Quirico, F Orso, S Cucinelli, M Paradzik… - Cellular and molecular …, 2022 - Springer
MicroRNAs (miRNAs) are small, non-coding RNAs about 22 nucleotides in length that regulate
the expression of target genes post-transcriptionally, and are highly involved in cancer …

[HTML][HTML] Integrin crosstalk contributes to the complexity of signalling and unpredictable cancer cell fates

I Samaržija, A Dekanić, JD Humphries, M Paradžik… - Cancers, 2020 - mdpi.com
Integrins are heterodimeric cell surface receptors composed of α and β subunits that control
adhesion, proliferation and gene expression. The integrin heterodimer binding to ligand …

[HTML][HTML] KANK2 links αVβ5 focal adhesions to microtubules and regulates sensitivity to microtubule poisons and cell migration

M Paradžik, JD Humphries, N Stojanović… - Frontiers in cell and …, 2020 - frontiersin.org
Integrins are heterodimeric glycoproteins that bind cells to extracellular matrix. Upon integrin
clustering, multimolecular integrin adhesion complexes (IACs) are formed, creating links to …

Apigenin, a dietary flavonoid, induces apoptosis, DNA damage, and oxidative stress in human breast cancer MCF-7 and MDA MB-231 cells

…, J Madunić, M Antunović, M Paradžik… - Naunyn-Schmiedeberg's …, 2018 - Springer
Apigenin is found in several dietary plant foods such as vegetables and fruits. To investigate
potential anticancer properties of apigenin on human breast cancer, ER-positive MCF-7 and …

[HTML][HTML] Stroma-derived miR-214 coordinates tumor dissemination

…, F Virga, D Dettori, A Dalmasso, M Paradzik… - Journal of Experimental …, 2023 - Springer
Background Tumor progression is based on a close interaction between cancer cells and
Tumor MicroEnvironment (TME). Here, we focus on the role that Cancer Associated …

Differential effects of integrin αv knockdown and cilengitide on sensitization of triple-negative breast cancer and melanoma cells to microtubule poisons

N Stojanović, A Dekanić, M Paradžik, D Majhen… - Molecular …, 2018 - ASPET
Low survival rates of patients with metastatic triple-negative breast cancer (TNBC) and
melanoma, in which current therapies are ineffective, emphasize the need for new therapeutic …

[HTML][HTML] Ancient origins of cytoskeletal crosstalk: Spectraplakin-like proteins precede the emergence of cortical microtubule stabilization complexes as crosslinkers

T Paradžik, II Podgorski, T Vojvoda Zeljko… - International journal of …, 2022 - mdpi.com
Adhesion between cells and the extracellular matrix (ECM) is one of the prerequisites for
multicellularity, motility, and tissue specialization. Focal adhesions (FAs) are defined as protein …

[HTML][HTML] Sirt3 exerts its tumor-suppressive role by increasing p53 and attenuating response to estrogen in MCF-7 cells

M Pinterić, II Podgorski, MP Hadžija, V Filić, M Paradžik… - Antioxidants, 2020 - mdpi.com
Estrogen (E2) is a major risk factor for the initiation and progression of malignancy in estrogen
receptor (ER) positive breast cancers, whereas sirtuin 3 (Sirt3), a major mitochondrial …

Gene expression in formalin-fixed paraffin-embedded lymph nodes

M Antica, M Paradzik, S Novak, S Dzebro… - Journal of immunological …, 2010 - Elsevier
Elucidation of molecular pathways involved in development of human lymphoma requires
efficient methods for tackling gene expression in lymph nodes. Expression studies of …

[HTML][HTML] The Tongue Squamous Carcinoma Cell Line Cal27 Primarily Employs Integrin α6β4-Containing Type II Hemidesmosomes for Adhesion Which Contribute to …

…, J Zha, K Čuljak, M Tomić, M Paradžik… - Frontiers in cell and …, 2021 - frontiersin.org
Integrins are heterodimeric cell surface glycoproteins used by cells to bind to the extracellular
matrix (ECM) and regulate tumor cell proliferation, migration and survival. A causative …