According to Genome Sequencing Project statistics (http://www. ncbi. nlm. nih. gov/genomes/static/gpstat.
html), as of February 16, 2012, complete gene sequences have become …

M2-polarized, pro-tumoral tumor-associated macrophages (TAMs) express the interleukin-4
receptor (IL4R) at higher levels compared with M1-polarized, anti-tumoral macrophages. In …

The mutation or overexpression of α-synuclein protein plays a pivotal role in the pathogenesis
of Parkinson’s disease. In our preliminary experiments, we found that α-synuclein induced …

Human cytomegalovirus encodes an unusual protein kinase, UL97, that activates the established
antiviral drug ganciclovir and is specifically inhibited by a new antiviral drug, maribavir. …

To identify biomarker candidates associated with early IgA nephropathy (IgAN) and thin
basement membrane nephropathy (TBMN), the most common causes presenting isolated …

The nuclear lamina is a major obstacle encountered by herpesvirus nucleocapsids in their
passage from the nucleus to the cytoplasm (nuclear egress). We found that the human …

Purpose: Currently, there are no molecular biomarkers for the early detection of breast
cancer. This study focused on identifying surface proteins found on circulating extracellular …

Inhibitors of the secretion of cancer exosomes, which promote cancer progression and
metastasis, may not only accelerate exosome biology research but also offer therapeutic benefits …

Extracellular vesicles (EVs) secreted from cancer cells have potential for generating cancer
biomarker signatures. Fibronectin (FN) was selected as a biomarker candidate, due to the …

Glucose homeostasis is maintained by the orchestration of peripheral glucose utilization
and hepatic glucose production, mainly by insulin. In this study, we found by utilizing a …