Approximately 20% of a dose of estragole, a naturally occurring flavoring agent, was excreted
in the urine of outbred male CD ® -1 mice as a conjugate (presumably the glucuronide) of …

The circadian clock plays a significant role in many aspects of female reproductive biology,
including estrous cycling, ovulation, embryonic implantation, onset of puberty, and parturition. …

The frequency and pattern of mutations at codon 61 of the c-Ha-ras gene have been analyzed
in 195 liver tumors and 132 precancerous liver lesions from various rodent strains with …

… Drinkwater, in preparation). We observed that the major difference between these two
strains was in the rate of growth of the pre-neoplastic lesions; these data indicate that the Hcs …

Tfm (testicular feminization) mutant mice lack functional androgen receptors. By studying
liver tumor development in Tfm mice, we have shown that the greater susceptibility of male …

Simple Summary The hormone estrogen is well known for its role in promoting breast and
ovarian cancer. Estrogen has the opposite effect on the liver, which it protects from cancer. We …

10.7554/eLife.09305.001 A cross-campus, cross-career stage and cross-disciplinary series
of discussions at a large public university has produced a series of recommendations for …

… Drinkwater, NR Genetic control of hepatocarcinogenesis in inbred mice. … Kemp, CJ, and
Drinkwater, NR The androgen receptor and liver tumor development in mice. In: T. Slaga and F. …

We have previously shown that C3H/HeJ male mice are 20-fold more susceptible to the
induction of liver tumors by N -ethyl- N -nitrosourea (ENU) than are C57BL/6J male mice and …

We set out to better understand the signal transduction pathways that mediate liver tumor
promotion by 2,3,7,8-tetrachlorodibenzo-p-dioxn (“dioxin”). To this end, we first employed …