Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease

N Itoh, DM Ornitz - The Journal of Biochemistry, 2011 - academic.oup.com
… However, we have observed that ketogenesis is not impaired in Fgf21 knockout mice fed
a ketogenic diet (N. Itoh et al., unpublished data). Fgf23 knockout mice survive until birth, but …

Carcinogenicity and modification of the carcinogenic response by BHA, BHT, and other antioxidants

N Ito, S Fukushima, H Tsuda - CRC Critical reviews in Toxicology, 1985 - Taylor & Francis
… Male hamsters given BHA for 24 weeks also developed papilloma showing downward
growth into the submucosa of the forestomach. These results indicate that BHA should be …

Brachial-ankle pulse wave velocity and the risk prediction of cardiovascular disease: an individual participant data meta-analysis

…, T Ohkubo, H Watada, M Munakata, M Ohishi, N Ito… - …, 2017 - Am Heart Assoc
… When the baPWV values were classified into quintiles, the multivariable-adjusted hazard
ratio for CVD increased significantly as the baPWV quintile increased. The hazard ratio in the …

Lethal effect of the anti-Fas antibody in mice

…, A Matsuzawa, T Kasugai, Y Kitamura, N Itoh… - Nature, 1993 - nature.com
… Calcium depletion of a lymphocyte cell line caused the messenger to be released from
intracellular organelles into the cytoplasm and to a much lesser extent into the extracellular …

Studies on antioxidants: their carcinogenic and modifying effects on chemical carcinogenesis

N Ito, M Hirose, S Fukushima, H Tsuda, T Shirai… - Food and Chemical …, 1986 - Elsevier
N-methyl-N′-nitro-N-nitrosoguanidine or N-methylnitrosourea (MNU) and enhanced urinary
bladder carcinogenesis initiated by MNU or N-butyl-N… or N-ethyl-N hydroxyethylnitrosamine …

Novel thioether bond revealed by a 1.7 Ĺ crystal structure of galactose oxidase

N Ito, SEV Phillips, C Stevens, ZB Ogel, MJ McPherson… - Nature, 1991 - nature.com
GALACTOSE oxidase is an extracellular enzyme secreted by the fungus Dactylium dendroides.
It is monomeric, with a relative molecular mass of 68,000, catalyses the stereospecific …

[HTML][HTML] Homophilic complex formation of MT1‐MMP facilitates proMMP‐2 activation on the cell surface and promotes tumor cell invasion

Y Itoh, A Takamura, N Ito, Y Maru, H Sato… - The EMBO …, 2001 - embopress.org
… transmembrane/cytoplasmic domain of NGFR (MT1‐F/NGFR, MT1Cat‐F/NGFR, MT1PEX‐F/NGFR
or MT4PEX‐F/NGFR, respectively) were also generated by PCR and subcloned into

Crystal structure at 1.92 Ĺ resolution of the RNA-binding domain of the U1A spliceosomal protein complexed with an RNA hairpin

C Oubridge, N Ito, PR Evans, CH Teo, K Nagai - Nature, 1994 - nature.com
… Here we describe the crystal structure of the complex between the N-terminal RNP domain
… Structure determination An extensive crystallization search was carried out with various N-…

Carcinogenicity of butylated hydroxyanisole in F344 rats

N Ito, S Fukushima, A Haqlwara… - Journal of the …, 1983 - academic.oup.com
… (36) MAKIURA S, AOEH, SUGIHARA S, HIRAO K, ARAI M, ITo N. Inhibitory effect of
polychlorinated biphenyls on liver tumorigenesis in rats treated with 3'-methyl-4-…

Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung

S Bellusci, J Grindley, H Emoto, N Itoh… - …, 1997 - journals.biologists.com
… Consistent with the findings of Nogawa and Itoh (1995) we find that culturing lung tissue
in collagen matrix does not result in the outgrowth of endodermal buds, whereas Matrigel is …