Phosphorylation of AMPA receptors: mechanisms and synaptic plasticity
JQ Wang, A Arora, L Yang, NK Parelkar, G Zhang… - Molecular …, 2005 - Springer
The ionotropic α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor is
densely distributed in the mammalian brain and is primarily involved in mediating fast …
densely distributed in the mammalian brain and is primarily involved in mediating fast …
Glutamate signaling to Ras-MAPK in striatal neurons: mechanisms for inducible gene expression and plasticity
JQ Wang, Q Tang, NK Parelkar, Z Liu, S Samdani… - Molecular …, 2004 - Springer
Extracellular signals can regulate mitogen-activated protein kinase (MAPK) cascades through
a receptor-mediated mechanism in postmitotic neurons of adult mammalian brain. Both …
a receptor-mediated mechanism in postmitotic neurons of adult mammalian brain. Both …
[PDF][PDF] Modulation of D2R-NR2B interactions in response to cocaine
…, M Wang, HX Lan, MH Li, GC Zhang, NK Parelkar… - Neuron, 2006 - cell.com
Dopamine-glutamate interactions in the neostriatum determine psychostimulant action, but
the underlying molecular mechanisms remain elusive. Here we found that dopamine …
the underlying molecular mechanisms remain elusive. Here we found that dopamine …
Phosphorylation of glutamate receptors: a potential mechanism for the regulation of receptor function and psychostimulant action
JQ Wang, X Liu, G Zhang, NK Parelkar… - Journal of …, 2006 - Wiley Online Library
… The N-terminus of a given subunit is located extracellularly and the C-terminus intracellularly.
The N-terminus and an extracellular loop between M3 and M4 specify the protein domain …
The N-terminus and an extracellular loop between M3 and M4 specify the protein domain …
[HTML][HTML] PKCλ/ι signaling promotes triple-negative breast cancer growth and metastasis
…, SR Stecklein, B Saha, N Parelkar… - Cell Death & …, 2014 - nature.com
Triple-negative breast cancer (TNBC) is a distinct breast cancer subtype defined by the
absence of estrogen receptor (ER), progesterone receptor (PR) and epidermal growth factor …
absence of estrogen receptor (ER), progesterone receptor (PR) and epidermal growth factor …
In vivo regulation of Homer1a expression in the striatum by cocaine
GC Zhang, LM Mao, XY Liu, NK Parelkar, A Arora… - Molecular …, 2007 - ASPET
The glutamate receptor adaptor protein Homer is concentrated in the postsynaptic density of
excitatory synapses and is critical for normal operation of synaptic transmission. In this study…
excitatory synapses and is critical for normal operation of synaptic transmission. In this study…
The protein phosphatase 1/2A inhibitor okadaic acid increases CREB and Elk‐1 phosphorylation and c‐fos expression in the rat striatum in vivo
ES Choe, NK Parelkar, JY Kim, HW Cho… - Journal of …, 2004 - Wiley Online Library
… ,5‐dihydroxyphenylglycine (DHPG) at 100 and 250 nm also increased CREB and Elk‐1
phosphorylation. Pre‐treatment of okadaic acid (0.05 nm) did not alter DHPG‐induced increases …
phosphorylation. Pre‐treatment of okadaic acid (0.05 nm) did not alter DHPG‐induced increases …
Protein Kinase A–Phosphorylated KV1 Channels in PSD95 Signaling Complex Contribute to the Resting Membrane Potential and Diameter of Cerebral Arteries
CL Moore, PL Nelson, NK Parelkar, NJ Rusch… - Circulation …, 2014 - Am Heart Assoc
… K V 1-C consists of the final 10 amino acids of the C terminus of K V 1.2α attached to an N
terminus HIV-tat sequence (NH 3 -YGRKKRRQRRR) to confer membrane permeability. An N …
terminus HIV-tat sequence (NH 3 -YGRKKRRQRRR) to confer membrane permeability. An N …
A novel, unusually efficacious duocarmycin carbamate prodrug that releases no residual byproduct
AL Wolfe, KK Duncan, NK Parelkar… - Journal of Medicinal …, 2012 - ACS Publications
… subjected to Boc deprotection with 4 N HCl in EtOAc and immediate N-acylation with 17, …
Both (+)- and ent-(−)-6 and their N-Boc precursors 16 were tested for cell growth inhibition in a …
Both (+)- and ent-(−)-6 and their N-Boc precursors 16 were tested for cell growth inhibition in a …
Hyperbaric oxygen improves engraftment of ex-vivo expanded and gene transduced human CD34+ cells in a murine model of umbilical cord blood transplantation
OS Aljitawi, Y Xiao, JD Eskew, NK Parelkar… - Blood Cells, Molecules …, 2014 - Elsevier
… Unless otherwise indicated, mice (n = 4 for each group for most time points) were imaged
1 day prior to their euthanization using IVIS Spectrum imaging unit. The following post-…
1 day prior to their euthanization using IVIS Spectrum imaging unit. The following post-…