Orally administered berberine modulates hepatic lipid metabolism by altering microbial bile acid metabolism and the intestinal FXR signaling pathway

…, J Shen, P Wang, S Feng, F Fei, J Guo, J He, N Aa… - Molecular …, 2017 - ASPET
Previous studies suggest that the lipid-lowering effect of berberine (BBR) involves actions
on the low-density lipoprotein receptor and the AMP-activated protein kinase signaling …

Acupuncture therapy for the treatment of stable angina pectoris: an updated meta-analysis of randomized controlled trials

…, H Meng, MR Khurwolah, J Liu, H Tang, N Aa… - … therapies in clinical …, 2019 - Elsevier
Background and purpose Stable angina pectoris is a common symptom imperiling patients’
life quality. The purpose of this meta-analysis is to assess the effectiveness of acupuncture …

[HTML][HTML] Hypoxia-inducible factor 1 alpha (HIF-1α)/vascular endothelial growth factor (VEGF) pathway participates in angiogenesis of myocardial infarction in muscone …

Y Du, Y Ge, Z Xu, N Aa, X Gu, H Meng… - … medical journal of …, 2018 - ncbi.nlm.nih.gov
Background Angiogenesis plays a crucial role in myocardial infarction (MI) treatment by
ameliorating myocardial remodeling, thus improving cardiac function and preventing heart failure…

[HTML][HTML] Muscone improves cardiac function in mice after myocardial infarction by alleviating cardiac macrophage-mediated chronic inflammation through inhibition of …

Y Du, X Gu, H Meng, N Aa, S Liu, C Peng… - American journal of …, 2018 - ncbi.nlm.nih.gov
Muscone is the main active monomer of traditional Chinese medicine musk. Previous studies
have reported a variety of beneficial effects of muscone. However, the effects of muscone …

[HTML][HTML] Compound danshen dripping pills modulate the perturbed energy metabolism in a rat model of acute myocardial ischemia

J Guo, Y Yong, J Aa, B Cao, R Sun, X Yu, J Huang… - Scientific Reports, 2016 - nature.com
The continuous administration of compound danshen dripping pills (CDDP) showed good
efficacy in relieving myocardial ischemia clinically. To probe the underlying mechanism, …

Quantitative analysis of 20 purine and pyrimidine metabolites by HILIC-MS/MS in the serum and hippocampus of depressed mice

Z Lu, S Li, N Aa, Y Zhang, R Zhang, C Xu… - … of Pharmaceutical and …, 2022 - Elsevier
Purine and pyrimidine metabolism are vital metabolic pathways in the development, proliferation
or repairment of cells or tissues associated with various diseases. Here, a simple, all-in-…

[HTML][HTML] Pharmacokinetic and metabolomic analyses of the neuroprotective effects of salvianolic acid A in a rat ischemic stroke model

S Feng, N Aa, J Geng, J Huang, R Sun, C Ge… - Acta Pharmacologica …, 2017 - nature.com
… Ji-ye AA, Zhi-jian YANG and Guang-ji WANG designed this study; Si-qi FENG, Nan AA and
… the data; Ji-ye AA, Si-qi FENG and Nan AA prepared the manuscript; Guang-ji WANG, Ji-ye …

[HTML][HTML] Protective effects of sodium tanshinone IIA sulfonate on cardiac function after myocardial infarction in mice

P Wu, Y Du, Z Xu, S Zhang, J Liu, N Aa… - American Journal of …, 2019 - ncbi.nlm.nih.gov
Sodium tanshinone IIA sulfonate (STS), a water-soluble derivative of tanshinone IIA, has
been used in traditional Chinese medicine for many years. Many experiments have …

[HTML][HTML] Compound danshen dripping pills normalize a reprogrammed metabolism of myocardial ischemia rats to interpret its time-dependent efficacy in clinic trials: a …

N Aa, JH Guo, B Cao, RB Sun, XH Ma, Y Chu, SP Zhou… - Metabolomics, 2019 - Springer
Introduction Clinical trials of Compound danshen dripping pills (CDDP) indicated distinct
improvement in patients with chronic stable angina. Daily fluctuation of therapeutic effect …

Machine learning and augmented human intelligence use in histomorphology for haematolymphoid disorders

A Nanaa, Z Akkus, WY Lee, L Pantanowitz, ME Salama - Pathology, 2021 - Elsevier
Advances in digital pathology have allowed a number of opportunities such as decision
support using artificial intelligence (AI). The application of AI to digital pathology data shows …