… Nicolás Di Siervi , Nicolás Di Siervi … Data were analysed mainly by two-way ANOVA blocking
by bull (Di Rienzo JA, Casanoves F., Balzarini MG, Gonzalez L., Tablada M., Robledo CW …

XPO1 regulates the dynamic ribonucleoprotein nuclear export in response to genotoxic
stress to support tolerance and can be targeted to enhance the sensitivity of cancer cells to …

Background Cestodes are a diverse group of parasites, some of them being agents of
neglected diseases. In cestodes, little is known about the functional properties of G protein …

Pancreatic cancer is one of the most lethal types of tumors with no effective therapy available;
is currently the third leading cause of cancer in developed countries; and is predicted to …

Several epidemiologic studies have revealed strong inverse associations between metformin
use and risk of colorectal cancer development. Nevertheless, the underlying mechanisms …

The melanocortin 4 receptor (MC4R) is a G protein-coupled receptor (GPCR) that is
expressed in several brain nuclei playing a crucial role in the regulation of energy balance …

Recent findings show that MRP4 is critical for pancreatic ductal adenocarcinoma (PDAC) cell
proliferation. Nevertheless, the significance of MRP4 protein levels and function in PDAC …

Kidney cancer accounts for 2.5% of all cancers, with an annual global incidence of almost
300,000 cases leading to 111,000 deaths. Approximately 85% of kidney tumors are renal cell …

The β-blocker propranolol (PROP) has been proposed as a repurposed treatment for breast
cancer. The similarity of action between β-agonists and antagonists found on breast cells …

Mammalian spermatozoa must undergo biochemical and structural changes to acquire the
capacity for fertilization, in a process known as capacitation. Activation of PKA enzymes is …