User profiles for Nino Zavradashvili
Nino Zavradashviliresearch scientist at the institute of chemistry and molecular engineering, Agricultural … Verified email at agruni.edu.ge Cited by 172 |
Artificial polymers made of α-amino acids-poly (amino acid) s, pseudo-poly (amino acid) s, poly (depsipeptide) s, and pseudo-proteins
N Zavradashvili, J Puiggali… - Current pharmaceutical …, 2020 - ingentaconnect.com
Degradable polymers (DPs) - “green materials” of the future, have an innumerable use in
biomedicine, particularly in the fields of tissue engineering and drug delivery. Among these …
biomedicine, particularly in the fields of tissue engineering and drug delivery. Among these …
Library of cationic polymers composed of polyamines and arginine as gene transfection agents
Combinatorially synthesized materials, especially cationic polymers (CPs), with gene
transfection function hold great promise in nanotechnology. However, the main limitations of the …
transfection function hold great promise in nanotechnology. However, the main limitations of the …
Arginine-based biodegradable ether–ester polymers with low cytotoxicity as potential gene carriers
The success of gene therapy depends on safe and effective gene carriers. Despite being
widely used, synthetic vectors based on poly(ethylenimine) (PEI), poly(l-lysine) (PLL), or poly(l-…
widely used, synthetic vectors based on poly(ethylenimine) (PEI), poly(l-lysine) (PLL), or poly(l-…
Oligoarginine peptides, a new family of nicotinic acetylcholine receptor inhibitors
Many peptide ligands of nicotinic acetylcholine receptors (nAChRs) contain a large number
of positively charged amino acid residues, a striking example being conotoxins RgIA and …
of positively charged amino acid residues, a striking example being conotoxins RgIA and …
Amino acid based epoxy-poly (ester amide) s—A new class of functional biodegradable polymers: Synthesis and chemical transformations
N Zavradashvili, G Jokhadze… - … Science, Part A, 2013 - Taylor & Francis
A new class of biodegradable functional polymers – epoxy-poly(ester amide)s (EPEAs), was
synthesized for the first time on the basis of naturally occurring α-amino acids, fatty diols …
synthesized for the first time on the basis of naturally occurring α-amino acids, fatty diols …
Cell compatible arginine containing cationic polymer: one-pot synthesis and preliminary biological assessment
Synthetic cationic polymers are of interest as both nonviral vectors for intracellular gene delivery
and antimicrobial agents. For both applications synthetic polymers containing guanidine …
and antimicrobial agents. For both applications synthetic polymers containing guanidine …
[HTML][HTML] New 1,2,3-Triazole Containing Polyesters via Click Step-Growth Polymerization and Nanoparticles Made of Them
High-molecular-weight AA-BB-type aliphatic polyesters were synthesized via Cu(I)-catalyzed
click step-growth polymerization (SGP) following a new synthetic strategy. The synthesis …
click step-growth polymerization (SGP) following a new synthetic strategy. The synthesis …
Optically Active Polymers with Cationic Units Connected through Neutral Spacers: Helical Conformation and Chirality Transfer to External Molecules
Y Wang, N Zavradashvili, Y Wang, A Pietropaolo… - …, 2020 - ACS Publications
Cationic chiral polymers consisting of a chiral “Arg monomeric unit” consisting of two l-arginine
moieties joined together through an oxyhexane-1,6-diyloxy spacer unit and achiral “Sp …
moieties joined together through an oxyhexane-1,6-diyloxy spacer unit and achiral “Sp …
New cationic polymers composed of non-proteinogenic α-amino acids
N Zavradashvili, G Otinashvili, T Kantaria… - Advanced Materials …, 2021 - taylorfrancis.com
The importance of cationic polymers (CPs) is universally recognized because they exhibit
unique biological properties; promote cell penetration of various molecules and nano-…
unique biological properties; promote cell penetration of various molecules and nano-…
[PDF][PDF] Synthesis of Biomimetic Polymers Based on Nonproteinogenic α-Amino Acids
N Zavradashvili, G Otinashvili, D Tugushi… - Bull. Georg. Natl …, 2021 - researchgate.net
Materials and Methods Materials. 1, 6-hexanediol, p-toluenesulfonic acid monohydrate (TosOH.
H2O), cyclohexane, sebacic acid (SA), phosphorous pentachloride, dichloromethane (…
H2O), cyclohexane, sebacic acid (SA), phosphorous pentachloride, dichloromethane (…