Identification of the growth hormone-releasing peptide binding site in CD36: a photoaffinity cross-linking study

A Demers, N McNICOLL, M Febbraio… - Biochemical …, 2004 - portlandpress.com
The GHRPs (growth hormone-releasing peptides) are a class of small synthetic peptides
known to stimulate GH release through binding of a G-protein-coupled receptor (designated …

Atrial natriuretic factor R1 receptor from bovine adrenal zona glomerulosa: purification, characterization, and modulation by amiloride

S Meloche, N McNicoll, B Liu, H Ong, A De Lean - Biochemistry, 1988 - ACS Publications
Revised Manuscript Received June 13, 1988 abstract: The atrial natriuretic factor (ANF) R!
receptor from bovine adrenal zona glomerulosa was solubilized withTriton X-100 and purified …

Direct β-Adrenergic Stimulation of Aldosterone Secretion in Cultured Bovine Adrenal Subcapsular Cells

ADE LÉAN, K RACZ, N MCNICOLL… - …, 1984 - academic.oup.com
Primary culture of bovine adrenal subcapsular cells was used to investigate direct effects of
catecholamines on aldosterone secretion. Cells dispersed with collagenase and DNAse and …

Allosteric modulation by ATP of the bovine adrenal natriuretic factor R1 receptor functions

L Larose, N McNicoll, H Ong, A De Lean - Biochemistry, 1991 - ACS Publications
Laboratory of Molecular Pharmacology, Clinical Research Institute of Montreal, Department
of Pharmacology and Faculty of Pharmacy, University of Montreal, Montreal, Quebec, …

Atrial natriuretic peptide‐dependent photolabeling of a regulatory ATP‐binding site on the natriuretic peptide receptor‐A

S Joubert, C Jossart, N McNicoll… - The FEBS journal, 2005 - Wiley Online Library
The natriuretic peptide receptor‐A (NPR‐A) is composed of an extracellular ligand‐binding
domain, a transmembrane‐spanning domain, a kinase homology domain (KHD) and a …

[HTML][HTML] Natriuretic peptide receptor A activation stabilizes a membrane-distal dimer interface

A De Léan, N McNicoll, J Labrecque - Journal of Biological Chemistry, 2003 - ASBMB
We have shown previously (Rondeau, J.-J., McNicoll, N., Gagnon, J., Bouchard, N., Ong, H.,
and De Léan, A. (1995) Biochemistry34, 2130–2136) that atrial natriuretic peptide (ANP) …

Glycosylation of asparagine 24 of the natriuretic peptide receptor-B is crucial for the formation of a competent ligand binding domain

R Fenrick, N Bouchard, N McNicoll… - Molecular and cellular …, 1997 - Springer
UV cross-linking studies of the natriuretic pepti de receptor- B (NPR-B )using radio labeled C-type
natriuretic peptide (CNP) indicate that onlyfully glycosylated receptors are capable of …

Glycosylation is critical for natriuretic peptide receptor-B function

R Fenrick, N McNicoll, A De Léan - Molecular and cellular biochemistry, 1996 - Springer
Co-transfection of a truncated natriuretic peptide receptor-B (NPR-B) with the full length
receptor results in a decrease of 60–80% in wild-type receptor activity. This reduction correlates …

[HTML][HTML] Agonistic induction of a covalent dimer in a mutant of natriuretic peptide receptor-A documents a juxtamembrane interaction that accompanies receptor …

J Labrecque, J Deschênes, N McNicoll… - Journal of Biological …, 2001 - ASBMB
The natriuretic peptide receptor-A (NPR-A) is composed of an extracellular domain with a
ligand binding site, a transmembrane-spanning domain, a kinase homology domain, and a …

Localization by photoaffinity labeling of natriuretic peptide receptor-A binding domain

N McNicoll, J Gagnon, JJ Rondeau, H Ong… - Biochemistry, 1996 - ACS Publications
A portion of the ligand binding domain for atrial natriuretic peptide (ANP) was identified as an
affinity cross-linked proteolytic fragment of bovine adrenal natriuretic peptide receptor type-…