Can T cells be directly activated to de novo gene expression by gonadotropin-releasing
hormone-II (GnRH-II), a unique 10-amino-acid neuropeptide conserved through 500 million …

Gonadotropin-releasing hormone (GnRH) analogues are used for the treatment of breast,
prostate, and ovarian cancer. These analogues exert their antitumor effects indirectly by …

GnRH, the main regulator of reproduction, is produced in a variety of tissues outside of the
hypothalamus, its main site of synthesis and release. We aimed to determine whether GnRH …

The mammalian gonadotropin‐releasing hormone (GnRH‐I), which regulates reproduction,
was the first isoform of GnRH that was identified in mammals. Recently, we and others have …

Gonadotropin-releasing hormone-I (GnRH-I), present in the mammalian hypothalamus,
regulates reproduction. In this study we demonstrate, for the first time, that an additional isoform …

Photodynamic therapy uses a combination of light, oxygen, and a photosensitizer to induce
the death of malignant cells. To improve the selectivity of a photosensitizer toward cancerous …

Gonadotropin-releasing hormone (GnRH) is a decapeptide secreted to the pituitary where it
binds to specific receptors on the gonadotropes to regulate gonadotropic hormones (…

The high concentration of gonadotropin-releasing hormone (GnRH) in milk of several species
implies that the mammary gland is either a site of synthesis for this neuropeptide or that it …

The gonadotropic hormones, luteinizing hormone (LH) and follicle-stimulating hormone (FSH)
are synthesized by and released from the anterior pituitary in response to the …

In an attempt to develop efficient chemotherapeutic agents targeted at malignant cells that
express receptors, we synthesized five new emodin derivatives and their gonadotropin-…