Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML

…, RY Wang, X Ling, O Frolova… - Blood, The Journal …, 2009 - ashpublications.org
SDF-1α/CXCR4 signaling plays a key role in leukemia/bone marrow microenvironment
interactions. We previously reported that bone marrow–derived stromal cells inhibit …

Comparative studies of bacteria with an atomic force microscopy operating in different modes

AV Bolshakova, OI Kiselyova, AS Filonov, OY Frolova… - Ultramicroscopy, 2001 - Elsevier
Escherichia coli bacterial cells of two strains JM109 and K12 J62 were imaged with atomic
force microscopy (AFM) in different environmental conditions. The AFM results show that the …

[HTML][HTML] A novel function for a ubiquitous plant enzyme pectin methylesterase: the host-cell receptor for the tobacco mosaic virus movement protein

YL Dorokhov, K Mäkinen, OY Frolova, A Merits… - FEBS letters, 1999 - Elsevier
Plant virus-encoded movement proteins promote viral spread between plant cells via
plasmodesmata. The movement is assumed to require a plasmodesmata targeting signal to …

Regulation of HIF-1α signaling and chemoresistance in acute lymphocytic leukemia under hypoxic conditions of the bone marrow microenvironment

O Frolova, I Samudio, JM Benito, R Jacamo… - Cancer biology & …, 2012 - Taylor & Francis
… REH and primary ALL cells were grown under normoxic (21% O 2 ) or hypoxic (1% O 2 ) …
or without MSC under normoxic (21% O 2 ) or hypoxic (1% O 2 ) conditions in the presence or …

The importance of the agrarian sector in the socio-economic systems development: methodological aspect

OY Frolova, LV Fomina… - IOP Conference Series …, 2020 - iopscience.iop.org
When solving problems of the socio-economic development, coordination of interaction
between various organizational systems becomes relevant. The quality of the socio-economic …

The personnel competence qualification formation in the agro-industrial complex production systems: managerial aspect

OY Frolova, LV Fomina… - IOP Conference Series …, 2020 - iopscience.iop.org
The employee's labor potential is not a constant value; it is permanently changing. Human
performance and employee's creativity are accumulated in the course of employment, they …

[HTML][HTML] Airborne signals from a wounded leaf facilitate viral spreading and induce antibacterial resistance in neighboring plants

…, TV Komarova, IV Petrunia, OY Frolova… - PLoS …, 2012 - journals.plos.org
Many plants release airborne volatile compounds in response to wounding due to pathogenic
assault. These compounds serve as plant defenses and are involved in plant signaling. …

Simultaneous inhibition of PDK1/AKT and Fms-like tyrosine kinase 3 signaling by a small-molecule KP372-1 induces mitochondrial dysfunction and apoptosis in acute …

…, W Zhang, Z Estrov, H Pelicano, D Harris, O Frolova… - Cancer research, 2006 - AACR
… an O 2 concentration of 220 μmol/L in air-saturated medium at 37C. The oxygen
consumption was rate is expressed as nanomoles of O 2 consumed as a function of time (nmol/L/min). …

[HTML][HTML] Mitochondrion-targeted antioxidant SkQ1 prevents rapid animal death caused by highly diverse shocks

…, KG Lyamzaev, MV Marey, MV Egorov, OJ Frolova… - Scientific Reports, 2023 - nature.com
… (A) Respiratory chains in mitochondria, reducing O 2 to H 2 O. (B) Respiratory chain in
mitochondria, reducing O 2 to H 2 O and superoxide. The specific inhibitors of complexes I and II …

Emotion, age, and gender classification in children's speech by humans and machines

H Kaya, AA Salah, A Karpov, O Frolova… - Computer Speech & …, 2017 - Elsevier
In this article, we present the first child emotional speech corpus in Russian, called “EmoChildRu”,
collected from 3 to 7 years old children. The base corpus includes over 20 K …