Protein phosphorylation

CS Rubin, OM Rosen - Annual review of biochemistry, 1975 - annualreviews.org
832 RUBIN & ROSEN phosphorylation at the molecular level has been ascertained: Similarly,
the classical phosphoproteins casein and phosvitin have been intensively studied for …

After insulin binds

OM Rosen - Science, 1987 - science.org
Three recent advances pertinent to the mechanism of insulin action include (i) the discovery
that the insulin receptor is an insulin-dependent protein tyrosine kinase, functionally related …

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

…, A Mason, PH Seeburg, C Grunfeld, OM Rosen… - Nature, 1985 - nature.com
We have deduced the entire 1,370-amino-acid sequence of the human insulin receptor
precursor from a single complementary DNA clone. The precursor starts with a 27-amino-acid …

Cloning and characterization of a cDNA encoding the rat brain glucose-transporter protein.

…, HC Haspel, OM Rosen - Proceedings of the …, 1986 - National Acad Sciences
Antibody raised against the human erythrocyte glucose transporter identified a recombinant
lambda gt11 bacteriophage in a cDNA library prepared from immunoselected polysomal …

[HTML][HTML] Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin.

…, R Gherzi, D Lebwohl, A Ullrich, OM Rosen - Journal of Biological …, 1987 - Elsevier
Transfected Chinese hamster ovary cell lines were developed that expressed equivalent
numbers of either normal human receptor or receptor that had alanine substituted for Lys-1018 …

Organelle relationships in cultured 3T3-L1 preadipocytes.

AB Novikoff, PM Novikoff, OM Rosen… - The Journal of cell …, 1980 - rupress.org
Rosen. 1978. Development of hormone receptors and hormonal responsiveness in vitro. …
Rosen. 1977. Acquisition of increased hormone sensitivity during in vitro adipocyte …

Archean and Early Proterozoic evolution of the Siberian craton: a preliminary assessment

OM Rosen, KC Condie, LM Natapov… - … in Precambrian geology, 1994 - Elsevier
Publisher Summary The Siberian craton extends from Lake Baikal on the south for over 2500
km to the Arctic Ocean on the north, and from the Yenisey River on the west to the Sea of …

Transformation of rat fibroblasts by FSV rapidly increases glucose transporter gene transcription

MJ Birnbaum, HC Haspel, OM Rosen - Science, 1987 - science.org
Elevation of glucose transport is an alteration common to most virally induced tumors. Rat
fibroblasts transformed with wild-type or a temperature-sensitive Fujinami sarcoma virus (FSV) …

Phosphorylation activates the insulin receptor tyrosine protein kinase.

OM Rosen, R Herrera, Y Olowe… - Proceedings of the …, 1983 - National Acad Sciences
Preparations of insulin receptor from cultured 3T3-L1 adipocytes and human placenta
previously was found to catalyze the phosphorylation of the 90,000-dalton component of the …

Growth factors rapidly induce expression of the glucose transporter gene.

Y Hiraki, OM Rosen, MJ Birnbaum - Journal of Biological Chemistry, 1988 - Elsevier
The expression of the gene encoding the facilitated glucose transporter (GT) protein was
studied in fibroblast cell lines. Addition of 15% calf serum to confluent BALB/c3T3, NIH3T3, or …