In liver and intestine, transporters play a critical role in maintaining the enterohepatic
circulation and bile acid homeostasis. Over the past two decades, there has been significant …

In addition to their classical roles as detergents to aid in the process of digestion, bile acids
have been identified as important signaling molecules that function through various nuclear …

… (for a recent review of BA metabolism, please see Dawson and Karpen(14)). For many years,
… 30) Ferrebee CB, Dawson PA. Metabolic effects of intestinal absorption and enterohepatic …

Objectives Our objective was to examine the effect of different fruits and their constituents on
P‐glycoprotein and organic anion transporting polypeptide (OATP) activities in vitro and on …

… Dawson,1,3 Cheryl Dissanayake,11,3 Valsamma Eapen,9,18,3 Helen S. Heussler,10,19,3
Allan F. … One or more of the authors of this paper received support from a program designed to …

Bile acids are transported across the ileal enterocyte brush border membrane by the well
characterized apical sodium-dependent bile acid transporter (Asbt) Slc10a2; however, the …

… This repeat sequence is a recent event in evolution and is not present in the mouse ileal Na
+ -bile acid cotransporter gene (Dawson, unpublished data). The effect of these sequences …

Active uptake of bile acids from the lumen of the small intestine is mediated by an ileal Na(+)-dependent
bile acid transport system. To identify components of this transport system, an …

… find impaired bile acid uptake in a number of adult patients with primary bile acid diarrhea
(12)… Oelkers, AL Craddock, and PA Dawson. 1994. Expression cloning and characterization of …

… Oelkers P, Kirby LC, Heubi JE, Dawson PA. Primary bile acid malabsorption caused by
mutations in the ileal sodium-dependent bile acid transporter gene (SLC10A2). J Clin Invest 1997…