In neurodegenerative disease or after brain injury, parenchymal cells in the central nervous
system are activated to produce inflammatory mediators, mainly consisting of cytokine-…

Vaccinations with amyloid-β peptide (AB) can dramatically reduce amyloid deposition in a
transgenic mouse model of Alzheimer's disease 1 . To determine if the vaccinations had …

The components of the adult extracellular matrix in the central nervous system form a lattice-like
structure that is deposited as perineuronal nets, around axon initial segments and as …

A novel bioactive peptide was recently isolated from ovine hypothalamus and was named
PACAP (pituitary adenylate cyclase-activating polypeptide). PACAP was present in two …

The extracellular matrix (ECM) in the central nervous system actively orchestrates and modulates
changes in neural structure and function in response to experience, after injury, during …

… Tatsuno I, Gottschall PE, Arimura A, Specific binding sites for pituitary adenylate cyclase
activating polypeptide (PACAP) in rat cultured astrocytes: molecular identification and …

… Hamilton microsyringe by polyethylene tubing (PE-20) at the point 13 mm plus the ventral
coordinate for OVLT or POA from the bottom tip so that the end of the polyethylene tubing was …

Growing evidence supports the notion of a functional relationship between the presence of
the β‐amyloid (Aβ) peptide and the production of inflammatory mediators in and around …

The present study was performed in order to clarify the mechanism by which interleukin-1 (IL-1)
activates the hypothalamic-pituitary-adrenal (HPA) axis. The iv administration of IL-1 into …

Systemic administration of anti-amyloid-β (Aβ) antibodies results in reduced parenchymal
amyloid but increased vascular amyloid and microhemorrhage in amyloid precursor protein (…